“near-significant”

Finally, we found a near-significant effect of antipsychotic drug use on mean caudate volume (β=0.016; P -value=6.71 × 10 −3 ), implying that caudate volume of depressed patients was greater as the percentage of patients taking antipsychotic drugs was higher ( Supplementary Figure S7 ).

Averaged across trajectories, the within-block rTMS effect was significant for MT+/V5 [ F (1, 17.8) = 40.1, p = 6 × 10 −6 ; p crit = 0.0028] and near-significant for its control site ( p = 0.007; p crit = 0.0057).

( 55 ) also examined NO and NOx, with significant and near-significant association between increase in NO (OR 1.46; 95% CI 1.11–1.93; p = 0.008) and NOx (OR 1.24, 95% CI 0.99–1.53; p = 0.052) concentrations and AE-IPF.

There were significant or near-significant correlations between improved BSA and hormone levels: estradiol levels ( p = 0.009, r = 0.648), estriol ( p = 0.06, r = 0.491), and the ratio of estrogen to progesterone ( p = 0.006, r = 0.671).

When a Bonferroni correction was made with statistical significance accepted at the p < 0.006 level, there was a statistically significant superiority in survival distributions for azathioprine over dapsone (χ 2 (1)=11.56; p = 0.001) as well as a near-significant superiority for MMF over dapsone (χ 2 (1)=6.83; p = 0.009) and for rituximab over dapsone (χ 2 (1)=6.20; p = 0.013).

On a significant or near-significant level patients showed decreases in beta3 and gamma power after verum as compared to sham stimulation (beta3: T = 2.900; df = 19; p = 0.009; gamma: T = 2.046; df = 19; p = 0.055) whereas controls showed power increases (beta3: T = 2.072; df = 19; p = 0.052; gamma: T = 2.201; df = 19; p = 0.040).

Both Groups 2 and 3 exhibited significant cellular regeneration and reductions in cell loss from the respiratory epithelial layer and near-significant reductions in ciliary loss and degeneration ( p = 0.009; p = 0.01).

For OS, significant or near-significant interactions ( p = 0.01 to 0.064) were observed for BMI and all body composition measures except IMAT, such that in the targeted therapy group, higher BMI, SAT, VAT, SM and SMI were associated with better OS (HRs 0.56 to 0.65), whereas no effect was seen in the immunotherapy group (all HRs near 1).

Using the Cox Proportional Hazards model, accounting for MMP-11 expression and other vital clinical and pathological prognostic factors, only two variables showed significant or near-significant associations with reduced DFS: elevated Ki67 (HR = 1.12, 95% CI [1.03–1.21], p = 0.01) and high MMP-11 expression (HR = 1.02, 95% CI [1.00-1.04], p = 0.05).

4C , purple line), comparison of microsaccade-rate timeseries in Pre-test versus Post-test 3 still revealed one significant cluster and one near-significant cluster in the following response time windows: 1,688–2,041 ms (Fig. 4C , gray-shaded area, p < 0.01) and 2,067–2,244 ms (Fig. 4C , lightly gray-shaded area, p = 0.055), respectively.

A near-significant outcome was observed for educational level within the cough cohort ( P = 0.01), whereas the control cohort exhibited a significant difference regarding marital status ( P = 0.000), as did the cough cohort ( P = 0.023).

Levene’s test for homogeneity of variance produced a near-significant result (F(3, 64) = 1.63, p < 0.01), suggesting that the variances across groups were marginally different and necessitating careful interpretation of results.

Significant or near-significant differences were noted for one question pertaining to vaccine attitudes/behaviors, regarding intention to get a vaccine if recommended by their doctor (p=0.01, V=0.39); one question related to vaccine knowledge, regarding need to get the influenza vaccine if received the previous year (p=0.05, V=0.18); and two questions regarding trust, namely trust in government influenza vaccination programs (p=0.04, V=0.19) and vaccine ingredients (p=0.06, V=0.18).

Furthermore, significant effects, or near-significant tendencies, of treatment and treatment × genotype interaction were evident for noradrenaline [treatment: F (1,26) = 7.443, p = 0.011; treatment × genotype: F (1,26) = 4.134, p = 0.052].

P200 There was a main effect of orientation ( F (1,17) = 28.09, p < .001, η 2 G = .120), a main effect of palate (F(1,17) = 18.06, p < .001, η 2 G = .017), and a near-significant orientation x palate interaction (F(1,17) = 8.06, p = .011, η 2 G = .005) on the amplitude of the P200.

Significant or near-significant changes over 12 months in PaO 2 were similar between groups: controls (ΔPaO 2 =−0.45 kPa, p=0.014); HFNC-treated, (ΔPaO 2 =−0.31 kPa, p=0.062).

Post hoc comparisons similarly identified significant to near significant group/genotype differences for average velocities in testing at 3, 5 and 12 months of age [t(9) = −1.50 to −3.32, p = 0.004–0.084, d = −0.48 to −1.05, Figure 2B ] and significant to near-significant group differences in distance traveled in testing at 3 and 5 months of age [t(9) = −1.56 to −2.58, p = 0.015–0.077, d = −0.49 to −0.82, Figure 2C ]. 3.4 Total time spent per maze compartments 3.4.1 Central platform From trial to trial, most rats spent about 45–55 s in the central platform of the maze.

An increased number of submovements showed a near-significant relation to intent classification ( z = 2.432, P = 0.015), while peak velocity was not related to communicative intent classification ( z = 0.924, P = 0.356).

One-way repeated measures ANOVA revealed a significant effect of treatment dose in CTL animals, with a significant reduction in demand elasticity (α) at the highest dose of agonist relative to vehicle, and a near-significant reduction with the lower dose (F (2,22) = 5.054, P=0.016; vehicle vs.

The normal-like samples did not stain for GLUT1, HK2, and LDHA, with the differences being significant and near-significant with regard to the LDHA and HK2 expression in the cancer sections (44.9% positivity for LDHA, p = 0.018; 35.5% positivity for HK2, p = 0.050).

51 Nevertheless, the near-significant reduction in family caregiver burden from T0 to T1 ( P = 0.019), approaching the adjusted significance threshold of 0.017, suggested a clinically meaningful impact.

Other significant or near-significant factors associated with increased risk of relapse in this model were summer birth season (aHR 1.63, CI 1.09–2.44, p = 0.02; compared with winter birth season) and treatment with mid-efficacy DMT (aHR 1.82, CI 0.93–3.55, p = 0.08; compared with no DMT use) or high-efficacy DMT (aHR 1.83, 0.92–3.64, p = 0.08; compared with no DMT use) (eTable 1, model 1).

All other colonies differed significantly from all colonies outside their clade ( F ST range 0.1–0.88, P < 0.01), with CR/COU being near-significant ( F ST = 0.13, P = 0.02).

Analyses of paired grafts in the same rabbits showed statistically significant or near-significant mean reductions of total and percentage ORO-positive intimal areas in HDAdApoAI grafts (19% and 14%; p = 0.02 and 0.05, respectively) ( Figures 4 E and 4F; Table 2 ).

Using two-tailed tests (as the assumptions for one-tailed tests were no longer valid), the MDD group showed significantly decreased Glu and Glx ( P =0.003, P =0.006, respectively) and the SZ group showed a near-significant decrease for Glu ( P =0.024).