“near significance”

However, from the medium effect size (d = 0.519) and low statistical power (1-β = 0.472), we concluded that the near significance is not effective enough.

Interestingly, we found that correlations to Ki-67 expression shifted with near significance ( 2 σ ) for multiple m/z peaks (Fisher transformed, one-sided z-statistics; Bonferroni corrected P-values) between CD3 − populations and the CD3 + population ( Fig 3h ), suggesting molecular candidates associated with proliferation in these cells.

Our GWAS analysis also suggested a genetic basis to ASI through the identification of a SNP of genomewide significance and a further eight SNPs of near significance occurring within the coding region of the binding protein, fox-1 homolog (RBFOX1) gene (see Fig 2A and 2B , Table 1 ).

Repeating the ancestry matching and 1:4 case to control ratio in DCM plus chronic disease, CLEC7A remained significantly overrepresented ( P = 0.0041; OR, 2.058 [95% CI, 1.26–3.37]) with p.I223S ( P = 0.0128; OR, 3.712 [95% CI, 1.32–10.426]) and p.Y238* ( P = 0.0564; OR, 1.735 [95% CI, 0.985–3.058]) at or near significance.

Thus, upregulated UCP3 driven increases in AMPK could be responsible for the reduced Fasn and Acaca (near significance) expression reported in the male KO-HF group in our study through phosphorylation and inhibition of ACACA [ 48 ].

this p-value is not approaching significance...missing zero? Regardless, it is not significant hence my suggestion is to remove this point (and any others about near significance like lines 164-169, 190-195).

Our findings showed that the positive association between subjective overload and psychological distress was different among countries, suggesting higher rate of intensity in Italy compared to China, India, and Israel (the UK was near significance with China and Israel).

Kidney renal papillary cell carcinoma (KIRP), uterine corpus endometrial cancers (UCECs), rectal adenocarcinoma (READ), cervical squamous cell cancers, breast cancers (BRCA) and liver hepatocellular carcinomas also all show a trend toward increased expression in mutant samples with KIRP displaying near significance (Figure S2A and B).

With a larger sample size, we suspect that several associations that are near significance, such as the association between h-index and various social media platforms among the overall cohort, would reach significance.

Although this did not reach conventional statistical significance ( P < 0.05), the near significance suggests a potential association that may support our conclusion regarding AsO 2 ’s relationship with macular RGC loss in regions with confirmed visual field damage.

Activity wavelet coherence analyses Since temperature range and temperature minimum were significant, and daylight near significance in the count model for activity, and latitude near significance in the count model and significant in the zero-inflation component, we also analyzed these three zeitgeber measures by latitude using wavelet coherence ( Figure 3 ).

MMP-3 was increased significantly in the label-free study and increased to near significance in the QconCAT study.

This near significance could be attributed to the accelerated wound healing properties of rhGFs, as indicated by the significantly reduced tissue healing times in the combined group.

Here, the nonparametric test outcomes hovered near significance, while the parametric test results undeniably attained a status of significance.

Moreover, the interactions between sex and treatment were significant or near significance for one-half of the offspring obesity outcomes (eTable 9 in Supplement 2 , last column).

Besides, there was a significant difference and a trend near significance for socioeconomic status and level of education among the quartiles of “fruits and dairy products” dietary pattern (Table 3 ).

This variability poses a challenge, especially for events near significance thresholds.

Urinary Sul-APAP and Mer-APAP, but not Glu-APAP were higher after 4 weeks of supplementation, when compared to week 0 and urine levels of unchanged APAP increased by 18% (near significance) [ 42 ].

Two other transcription factors, CTCF and FOXA1 , were at or near significance harboring 13 and 8 mutations, respectively.

Those SNPs showing significant (or near significance) associations in one of the obesity strata were selected for combination in the corresponding obesity-specific GRS (nobGRS and obGRS).

The screen pulled up seven contigs that mapped to RIPK2 most of which were not significant but six of the seven showed upregulation and near significance.

1 ). In the multivariate analysis, the preoperative tumor volume was statistically significant ( p = 0.014), and CRET was near significance in some models.

I would agree your findings are null even though you are near significance!

semiglobosa , the results indicated near significance for selection.

The near significance of this result indicates that with a larger sample size or a longer duration of study, this increase might reach statistical significance, which would have important implications for the potential benefits of immunonutrition in bolstering cellular immunity.