Barely Significant
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“might be significant”

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Sighted at

p=0.065p=0.54

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In the literature

Recently, Larramendy et al (1997) reported infre- quent gain of 1q material in malignant fibrous histiocytomas (MFHs), but with a more distal minimal common region, 1q24. It might be significant that many of the tumours with amplifica- tions of 1q are well-differentiated liposarcomas (WDLPS) and MFHs tumours that are often characterized by giant marker chro- mosomes containing amplified segments from various chromo- somes (Heim et al, 1987; Orndal et al, 1992; Dal Cin et al, 1993; Pedeutour et al, 1993; Nilbert et al, 1994).
These observations also have potential consequences for toxicological aspects of nanoparticles, with particular relevance to considerations of toxicity of fullerenes and carbon nanotubes, where, for example, lung surfactants and the latherin-related PLUNC proteins of the human oral and upper respiratory tract [25] , [26] , [27] , might be significant in the uptake, tissue penetration, and/or clearance of airborne particles.
As that had been mentioned previously, the dose of GBE used in the current and previous studies may not be directly translated to that in clinical situations since there might be significant variety in individual drug metabolism and accumulation effects of such kind of herb medicine in different person [ 12 , 13 ].