“might be significant”

However, due to cellular heterogeneity, particularly for cancer cells, there might be significant genetic differences in these cells.

Only one study evaluated the efficacy and adverse events of the two stages combined approach; thus, this finding might be significant for the treatment of subaxial cervical spine injury.

The key factors for this recent outbreak might be significant contact of humans with unknown pathogens and reservoir hosts following an increase in human activities such as agriculture in the region, which expose people to the wildlife.

The much larger sample size of non-Hispanic whites could mean much smaller standard error, and hence a coefficient that is not significant for foreign-born or US-born Chinese Americans might be significant for non-Hispanic whites.

The latest studies have revealed the ITRs to be insufficient compared with the Rep proteins in binding to cellular sites of DNA damage that might be significant in AAV2 genome integration ( 31 ).

3 , 4 Five patients had a positive GAD‐Ab 2–50 months before they needed intensive insulin therapy, indicating that GAD‐Ab testing during diabetes diagnosis after ART initiation might be significant in predicting a decrease in the endogenous insulin secretion.

In addition, we found that genotypes of the IL-1 gene cluster SNPs are associated with a higher production of the relative cytokines; in particular IL-1A rs1800587TT might be significant a risk factor for sepsis, septic shock and neurological symptoms.

These results indicated that different stress- and defense-related proteins were activated or inhibited in response to internal and external stress and stimulation during seed germination, and that there might be significant differences in the occurrence and establishment of defense systems in the process of germination.

Some studies have suggested that poor environmental sanitation and housing conditions, as well as lack of appropriate control measures might be significant risk factors for malaria parasite burden [ 9 ].

The small number of female patients might be insufficient to prove significance, and the effects of a FH might be significant in a study with a large number of patients.

The threshold of 0.25 was chosen as a conservative criterion to avoid excluding potentially important variables that might be significant after adjusting for confounders. 19 For categorical variables, thresholds were selected based on clinically meaningful cut-offs or distribution in the data.

In this study, we analyzed the well-recognized risk factors of LSCC–smoking and alcohol consumption, believing that these factors might be significant in individual prognosis.

3.4 Meta-regression analysis The meta-regression analysis, using the predefined potential sources of heterogeneity as covariates in the Moses–Shapiro–Littenberg model, indicated that the iFR cut-off value ( P < 0.05) might be significant predictors.

Furthermore, there might be significant inter-individual differences in how participants are able to express feelings through movement that would also be an interesting topic of future investigations.

The current study suggests that there might be significant interactions between gabapentinoids and opioids related to both opioid overdose and substance misuse that warrant further investigation.

From Figure 5 we find that even when the effects of changes in transcription initiation on the response of the biphasic amplitude filter are slight, the change in the fluctuations of the protein numbers of the output gene might be significant.

In particular, dosimetric improvements might be significant for less forgiving forms of treatment delivery such as stereotactic body radiotherapy.

These might be significant obstacles for any large-scale application of conventional photocatalytic oxidation in real wastewater treatment.

Furthermore, several phytomelatonin-rich extracts of plant antioxidants such as simple phenols, flavonoids, tocopherols, ascorbic acid, carotenoids, and others, might be significant for maintaining a proper cell redox balance.

Low nicotine levels administered chronically (for example, by the nicotine patch) may desensitize nAChRs [ 304 , 305 ]; therefore, nAChRs blockade might be significant in the manifestation of the influence of nicotinic substances on depressive symptoms.

A general recommendation therefore might be to simply repeat the analyses with other reference lags if researchers suspect that there might be significant structure at both l ̄ and − l ̄ , or to fix the reference lag to be, e.g., l * = ± ( l m a x + 1 ) , with l m a x the maximum lag tested for, for all lags considered.

There might be significant regional differences in the mortality rate and percentage of severe cases in different regions.

Only for RO 2 with specific structures such as HO-, allyl-, or acyl substituents, they might be significant at room temperature (see structure–activity discussions in ref. 16 and 19 ).

While the individual paths might not be significant, the indirect path itself might be significant due to non-zero correlation between the component paths.

There is an additional anisotropic contribution of the electron‐nucleus dipolar coupling which, in contrast to the PCSs, is averaged by MAS, but still might be significant for residues in close vicinity to the metal center at typical MAS frequencies used ( vide infra ).