To adjust for loss of follow-up, which may be significant in this cohort, a multilevel survival analysis will be conducted, with the outcome being time to first fall (and first fracture).
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In the literature
Therefore, attenuating inflammation in the brain during aging may be significant in supporting healthy aging.
Second, there may be significant gender differences in the relationships between the variables.
Furthermore, the possibility of impaired motor vehicle operation and psychomotor function has been pointed out ( Verster et al., 2014 ; Ayre et al., 2022 ), and there is concern that the effects on people’s social lives may be significant.
This suggests that there may be significant variation in the knowledge and understanding of BLS among different Arab countries, highlighting the need for targeted interventions to improve BLS knowledge in specific countries.
Our research results may be significant as they provide clinical evidence of no association between tumor microenvironment characteristics and PTC prognosis.
Our study may be significant for the immunotherapy guidance and prognosis prediction of LIHC.
We chose an analogous time in the previous year instead of the time immediately preceding the COVID-19 pandemic because there may be significant variation on seeking treatment over the course of the year, especially with respect to seasonal weather changes and seasonal travel of patients (especially elderly, retired patients) between regions of the United States.
This fact may be significant for therapy of atherosclerosis that is associated with gene expression due to hypomethylation of a gene's regulatory regions.
As we observed, there may be significant differences between trends modeled in absolute versus relative annual change.
In trials, especially when complex interventions are delivered to some patients whilst other patients receive standard care at the same site, the opportunity for contamination may be significant.
The result of this study may be significant as the inhibition of egg hatch is possibly an important method of reducing pasture contamination by the animals during grazing helping in the overall helminth control programme.
Therefore, by increasing attention to environmental effects and their epigenetic or cellular consequences, there may be significant opportunities for prevention (e.g., public health measures in pregnancy) or individualised treatments for people with neurodevelopmental disorders.
Regaining trust by acting transparently While the tactics described above are not new, their impact on the decision process may be significant, particularly considering the Commission's failure to propose the legislation it had committed to.
Additionally, gene expression in processes such as PLD may be significant, but additive or mildly synergistic in nature ( Figure 3—figure supplement 2 ), and thus may play a role in the non-synergistic outcomes of correlated monotherapies.
Such reframing may be significant for women navigating marianismo norms and for families equating institutional care with abandonment.
The cross-dose contribution is significant for bone marrow [ 45 ] and may be significant for kidneys if its self-absorbed dose is low or if the tumor burden is high [ 46 ].
The positive charge and branched structure of the arginine and lysine residues may be significant in the trafficking of GTs.
At the millimeter level of accuracy for position and 0.1 mm/yr for rate, long-term tilting of the antenna structure may be significant, as suggested by the pointing measurements of the KPGO antennas.
There may be significant scarring in this area.
Although the patient group unable to tolerate NIMV due to agitation is small, using ketamine to prevent the transition to invasive ventilation may be significant in terms of both cost savings and patient survival [ 16 ].
Such an attempt has been done in the article by Koneti et al ., where they report an experience of congenital portosystemic shunts from five Indian centers.[ 36 ] However, there may be significant heterogeneity in practices between various centers, in addition to the bias inherent to retrospective review of records.
Other unmodeled effects that may be significant are related to social behavior change due to the course of the epidemic (e.g. risk perception, change in the pattern of social iterations, mask use, etc.) [ 78 ], reinfections [ 51 ], etc.
Seems like overlap may be significant, and if so, this is likely an epigenetic mark of the metabolic shift than of any stress response or aging per se. 5) In Figure 1A, it is important to know when cell lysates were collected and how much glucose is present in the cultures at the time of collection.
Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .