“may be significant”

Such shifts may be significant, as they could influence how the protein engages with potential inhibitors.

However, it has been suggested that insect bites or, more often, the ingestion of food contaminated with infective fly-spot (faeces or regurgitate) from flies that have fed on dead rabbit carcasses, may be significant transmission routes in the field for wild rabbits [ 9 , 10 ].

Caution is advised when interpreting the results because these sites may be significant contributors to ventilator‐associated infections.

There may be significant gender differences in the incidence of F-PNETs over time.

The first and most important is that it has a retrospective design, and in retrospective studies, there may be significant data losses that will affect the results.

Unlike the circadian clock, which has a long period relative to the expected transcription and splicing times of its genes [ 4 ], the segmentation clock's relatively short period, in the order of an hour, suggests that gene length and the presence of introns may be significant for timing in this system [ 5 ].

While these problems may be significant in a linear, parametric modeling context, the approach outlined here is more robust to these types of problems due to the flexible way in which model covariates can interact and influence one another.

Naturally and at any age, there may be significant variations in AMH levels among women [ 12 , 13 , 19 ], however the greatest variability is seen in women aged ∼25 years.

In the literature there is also some evidence that in order to differentiate ULMS, adenomyosis and ULM, the evaluation of the endo/myometrial junctional zone may be significant, especially the vascular pattern between these two types of tissue, as was suggested by Fascilla et al.

circinelloides epimutants, along with transient mutants against FK506, suggests that RNAi-dependent epimutation may be significant mechanism of antifungal resistance for Mucorales .

The possible reason may be significant operative damage to neural tissue or development of retethering.

Although the 2.4 NTU average daily median in our data sits below that value, the frequent high turbidity events may be significant stressors, particularly when they coincide with high temperatures over summer.

There may be significant differences between rural and urban settings.

While the clinical implications of our findings may be significant, they must be interpreted with caution given the exploratory nature of the analysis.

Similar to our previous finding in an iron-catalysed hydrosilylation of olefins, 2 g there may be significant π–π interaction between the backbone of the 1,10-phenanthroline ligand and the aryl of the alkyne substrate, which leads the hydride to transfer to the alkyl substituent side of alkynes (as shown in the II-A model), and results in the observed regioselectivity.

Our analysis also indicates that certain characteristics of community members may be significant predictors of health state valuations.

benthamiana orthologue of Arabidopsis VAMP721 and VAMP722 (Table S1 ), which we previously used to validate RipD localization in vesicles within plant cells (Figure 3d ), suggesting that VAMPs may be significant interactors of RipD during R. solanacearum infection.

A French series reported recurrence rates of 67%, indicating that the relapse rate may be significant [ 7 ].

Increased expression of BAX and BAK may be significant as the products of these genes have been reported to be involved in the induction of apoptosis following treatment with anticancer agents ( Jones et al , 1998 ; Ionov et al , 2000 ; Zhang et al , 2000 ). cDNA microarray analysis of cell cycle and apoptosis gene expression following CDDP treatment G

Sulfamethoxazole levels below IC50s required to overcome malaria parasites with multiple antifolate resistance mutations may be significant.

The knowledge of the metabolic features governing cancer cell dormancy entry/escape may be significant in developing effective targeted therapies.

Moreover, our data suggests that the mitochondria and Golgi apparatus, which are critical subcellular organelles, may be significant treatment targets for ischemic stroke-induced ferroptosis.

This finding supports our qualitative results, which suggest that long distances and travel times to KP-friendly facilities may be significant barriers for some FSW and MSM.