“may be significant”

The variation in staining and fixation between different laboratories may be significant even if the internal quality control of each center is maintained.

DOACs are becoming more commonplace and the risk of progression of hemorrhage after ICH in patients taking these medications is not clearly understood but may be significant. 26–28 In order for any set of guidelines to be implemented, they must be generalizable across different providers and institutions.

Even when studies use the same term, such as ‘HS’, there may be significant variations in how this construct is operationalised and measured.

Likewise, there may be significant variability in groups, such as intra-group stigma and discrimination; future larger studies should explore intra-group differences in LGBT cultural competency.

These pathways may be significant in the development of COPD in mice induced by CS.

19 In addition to these structural changes, there may be significant inflammatory infiltration within the stroma, which often results from the chronic irritation caused by the tumor’s growth.

The inhibition of biofilm formation and the eradication of biofilms on surfaces covered by plant products may be significant in future techniques that prevent or treat biofilm-associated infections [ 81 ].

We discuss the significance of these findings in terms of biological examples of viability and fecundity selection, and speculate that the effect may be significant when factors such as gene migration maintain a degree of linkage disequilibrium.

Other effects are expected to be of less influence, such as the potential influence of photons (e.g., UV-induced surface hydroxylation 44 ), a thermal growth component during the plasma half-cycle, 28 and soft-saturation during the precursor step, where decomposition of Ti(NMe 2 ) 4 may be significant at high temperatures (e.g., at 300 °C). 45 By the aforementioned results it is concluded that, also under mild plasma conditions, ions have a strong impact on the film crystallinity and GPC during plasma ALD of TiO 2 .

This finding suggests that the involvement of ALKBH5 in cancer may be significant but baffling.

The losses are caused by the attenuation of the guided wave due to material properties and due to the radiation of a leaky wave into the surrounding medium, which in the case of surrounding liquids or a soil may be significant.

This supported our premise that the role of stochasticity in AMR-dynamics may be significant and it allows for a wide distribution of the trajectories of the resistant E. coli number and fraction during therapy ( Fig. 5 and 6 ).

We can detect regional lung function impairments (especially in PRISm patients) in patients with FEV1/FVC ≥ 0.7, which may be significant for early COPD diagnosis.

Thus, local resection by ESD may be significant for EGC patients with advanced malignancies in other organs.

Most systemic therapies carry a risk of pneumonitis which may be significant depending on the agents used and may be exacerbated if combined with radiotherapy.

Taking into account the high conservation of the CBP20 function and the position of the substituted amino acid, the described changes in the hvcbp20.ab structure may be significant for CBP20 functioning.

In addition, due to the different roles and responsibilities assigned to men and women by social expectations and norms, there may be significant gender differences in the impact of social support on fertility intentions [ 16 ].

The number of patients in this subgroup may be significant (in the LACC trial, 55% of patients with information on tumor size had tumors < 2 cm) [ 10 ].

The researchers pointed to the variants −1575 G/A (rs243866), −168 G/T and also −1306 C/T (rs243865) as those that may be significant in determining the factors of this disorder, the complication of which may be the development of type 2 diabetes and cardiovascular disease [ 22 , 23 , 24 , 25 ].

While this may be significant in the absolute sense, it's may not be a huge difference relative to the measured moduli of the two materials.

The influence of the reproductive life cycle of women, specifically the impact of hormonal fluctuations during puberty, during the menstrual cycle, during pregnancy and postpartum, and during the perimenopause period on mood may be significant.

P-selectin Glycoprotein Ligand-1 (PSGL-1) has been identified as a potential binding partner for VISTA under acidic conditions-common in TME- suggesting that VISTA-PSGL-1 interactions may be significant in regulating immune cell function under these conditions 58 , 59 .

These findings may be significant in uncovering the pathogenesis of AAK.

35 It may be significant to identify the group with better prognosis by extracting the cases with TLSs-high in the worse-prognosis disease, such as uterine leiomyosarcoma.

The metabolic load from apoptotic cell digestion may be significant in some contexts, as individual macrophages can contain up to 10 to 20 phagocytosed corpses [ 13 ].