“may be significant”

Although we did not investigate the origin of this association, this result suggest that cav-1 expression may be significant for sequestrating TACE within the caveolar network, placing the enzyme in proximity to its substrate.

The timing of the trend may be significant, occurring at a point of transition between, on the one hand, older, eighteenth-century ideas about polite appearance, with shaving regarded as an expression of manly self-control and authority, and, on the other, gradual moves towards a more physically rugged model.

Chemical enhancements and related quantum tunneling effects are not considered, although they may be significant at these dimensional scales.

Mentoring and career support programs ( 5 ) from medical schools may be significant in helping students navigate their career preferences and pipelines while aligning with the needs of the country and society.

The AUC of 0.663 indicates a moderate ability to differentiate AD from MCI, suggesting that while the model shows promise, there may be significant overlap in susceptibility values between the two groups.

However, high costs and the limited availability of robotic platforms may be significant disadvantages of RAA [ 9 ].

Research should examine broader cultural contexts, sample populations and environments in which coachability may be significant to learning and performance.

In many cases, the radiation burden to the patient and operative team may be significant.

However, PrEP has not been widely integrated into family planning services, especially in the Southern U.S., and data suggest there may be significant implementation challenges in this setting.

The BMA gives some examples in their safeguarding guidance including where a criminal offence has been committed, where there may be significant risk to another person, or where a suspected abusive adult is in a position of authority (p. 24) [ 8 ].

Although the rewards of private sector collaboration and financing may be significant, substantial risks may also arise.

It may be significant that GM-CSF effects appeared more favorable in the trials in which peptide antigens were admixed with GM-CSF [ 52–54 ), or antigen-loaded DC were admixed with GM-CSF [ 55–57 ], or GM-CSF was secreted by autologous or allogeneic melanoma cells [ 58–61 ].

Our demonstration here that the absence of PARP1 in human cells leads to aberrant telomere maintenance suggests that there may be significant long-term repercussions to the chemical inhibition of PARP1 in human cells that might not be immediately evident.

There may be significant divergences between the perceptions of speech therapists and parents or guardians or caregivers regarding the pragmatic skills of children with ASD.

Therefore, given the isoforms are expressed from distinct promoters, we hypothesized that there may be significant variation of isoform expression throughout the global population associated with the Fy - allele.

Although long QT syndrome runs in families, there may be significant variations in clinical features among family members due to variable penetrance (differing frequency of manifestation of genetic traits by individuals).

21 This may be significant when discussing risks of elective cardiac surgery to this younger patient population who generally experience greater baseline cognitive function and therefore potentially greater QOL.

This, in turn, indicates that youth and lack of experience may be significant factors contributing to the perception of psychosocial risk in nursing.

15 In light of the role that IRAK-M plays in limiting lymphoid follicle development, it may be significant that LTi cells have been demonstrated to express TLRs.

There are publications suggesting that certain polymorphisms in the TLR gene family may be significant in determining susceptibility to CCHF and the clinical course of the disease in patients in Türkiye [ 55 , 56 ].

2 , 12 However, the burden of an MDS misdiagnosis may be significant for both patients and clinicians, and therefore, it is mandatory to identify patients at risk for this rare condition, taking into consideration the presence of other disorders causing such peculiar morphologic features.

Thus, evaluating PD-L1 and TGF-β receptor I (TGF-βRI) expression during treatment may be significant for prognostic/prediction and better therapeutic definition.

The authors concluded that this correlation may be significant in studies with more patient numbers. 32 Similarly, we indicated no correlation of renalase with echocardiography parameters of left ventricular hyperthrophy or ejection fraction in our cohort.

There is evidence to suggest that among medical students empathy decreases as they progress throughout their degree, yet, contrastingly, among student pharmacists there may be significant increases in empathy scores as student pharmacists progress across the year levels of the degree [ 46 , 47 ].

This last factor may be significant as the more dispersed electrostatic attraction may stabilise the SmA phase less well to allow the formation of the columnar phase, which in this case has rectangular plane symmetry.