“may be significant”

Strain differences seem unlikely to account for the discrepant results since both transgenic lines were generated on an FVB/N background; however, it is possible that genetic drift and the level of PLN overexpression may be significant factors.

Although our effect estimates are small, they reflect a z score increase from every 10% UPF energy contribution and may be significant on a population level.

Additionally, there may be significant utility in the use of topical nasal treatments alongside NS that further improve CPAP tolerance and subjective quality of life in patients with OSA. 31 , 32 In our study, we observed a sex disparity for OSA patients that underwent NS within our cohort.

Realizing the clinical implications of raising AEA levels with inhibitors, the last sentence of our paper read: “The development of inhibitors that block the breakdown of anandamide may be significant therapeutically in any of the areas that Δ 9 -tetrahydrocannabinol and anandamide has been shown to play a role, including analgesia, mood, nausea, memory, appetite, sedation, locomotion, glaucoma, and immune function” (Koutek et al., 1994 ).

The course design challenge may be significant, given all the duties and responsibilities of today's college professor.

In greenhouses, the heat stress may be significant because solar heat is trapped inside, and the application of heat reduction measures that do not interfere with crop growth is difficult.

Moreover, they influence adipose tissue regulation by participating in adipogenesis and lipid and glucose metabolism, which may be significant in developing metabolic disorders such as obesity and insulin resistance [ 27 , 29 ].

However, the relationship between TRPS1 genotype and phenotype is not entirely consistent, and even among carriers of the same gene mutation, there may be significant differences in phenotype.

We were able to obtain excellent fits, which suggests that the tanh() model may have wider applicability to wedge-shaped gradient wettability systems, albeit with modifications for non-SLIP surfaces where contact line pinning may be significant.

Overall, our findings suggest that for governments aiming to support businesses during the pandemic, payroll tax cuts have attractive built-in targeting properties, which may be significant even in the presence of moderate levels of labor informality.

Although the mechanisms by which the UPS contributes to HGSOC have not been determined, the current study suggests that the role that the UPS plays in the Fanconi anemia pathway and in the cell cycle pathway may be significant in the progression of EOC.

mori with unrelated taxa within the Hysteriaceae in Clade A and D may be significant in that Hb. mori has long been regarded as a highly variable taxon ( Ellis & Everhart 1892 , Lohman 1933a ), resulting in the synonymy of no fewer than 30 names since its inception by Schweinitz in 1832 ( Zogg 1962 ).

In this context, investigating job insecurity, as perceived by deluxe hotel employees, and its negative effects may be significant in determining how industries can recover and how rapidly changing industries can be sustained in the future.

31 In order to simplify the fitting and analysis we have considered two limits of this general reaction network, differing in their mechanism of the secondary process: in the first case both fragmentation and secondary nucleation, which act in parallel, may be significant, but we assume that there is no significant saturation of secondary nucleation ( i.e.

38 Studies with next-generation sequencing have identified significant enrichment for mutations in genes involving histone modification in patients with CHD, especially H3K4 , H2K7 , H3K9 , and H3K27 , suggesting that histone modification may be significant in the pathology of isolated disease. 1 , 4 Investigation of chromatin remodeling in model organisms has shown that dynamic modification of chromatin structure plays an important role in the regulation of gene expression during heart development. 13 De novo mutations affecting chromatin regulation genes contribute to about 3% of the CHDs.

The pink1 gene is a sensitive marker of oxidative stress in zebrafish, and LGR effectively normalizes the consequences of mild oxidative stress, suggesting that the neuroprotective effects of pink1 and LGR may be significant and useful in drug development. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2013 Jun 12; Accepted 2013 Oct 21; Collection date 2013.

28 Therefore, these parameters may be significant to the efficiency of the light absorption process, which is particularly crucial if we would like to use TiO 2 NTs as a photoanode for the photoelectrochemical decomposition of water, as Fujishima and Honda reported for the first time in 1972. 37 At present, despite the fact that photoelectrochemical decomposition of water is a promising method for generating hydrogen, inexpensive and environmentally friendly materials based on TiO 2 structures are still being sought.

10 There may be significant differences between these European, Asian, American and African ethnic groups in terms of %BF cut-off point and fat distribution.

There is, at present, no evidence to determine the relative importance of the tubule system and of the surface membrane of the microvilli in the secretion of hydrochloric acid. However, it may be significant that the tubules are more closely associated with the mitochondria than are the microvilli.

Additionally, a robust analysis of occupational influence was not feasible due to the limited sample size of MSM in medical-related fields, although this factor may be significant. 29 Lastly, HPV vaccination willingness is a complex, multi-faceted construct involving personal, cultural, and economic considerations.

Upregulation of interferon and STING signaling with this combination treatment may be significant in enhancing the immunogenicity of DIPG cells to allow effective immunotherapy. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Collection date 2024 Jun.

In addition to patient safety benefits, there may be significant economic advantages associated with accurate adjustment of IOP in the operating theater.

It may be significant that both we and Guillou and Giles (1973) were unable to show any correlation between migration inhibition and tumour extent at operation.

The risk may be significant; heatstroke, for example, is associated with a mortality rate of 40 % [ 4 ] to 64 % [ 2 ].

In this regard, it may be significant that erythrocytes have been recently reported to contain a Mr 70,000 poly- peptide that cross-reacts specifically with antibodies to non- muscle caldesmon (11).