Particularly in MDS patients, there may be significant differences between clinical trial populations and patients in routine clinical care and registries, as the median age at diagnosis of MDS patients is around 76 years. 55 Additionally, specific outcomes may be more important for a specific patient subgroup.
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“may be significant”
In the literature
Subgroup considerations Geographical remote people The equipment and expertise likely to be required for using placental derived products may be significant and people living in rural and regional Australia may have difficulties in accessing it.
The fact that circulating ADMA is elevated preceding the onset of preeclampsia not only supports that elevated ADMA may be involved in the pathogenesis of preeclampsia, but more importantly suggests that measuring of ADMA may be significant for the early identification of pregnant women who are at risk for preeclampsia.
The effect of this intervention on the workflow factors presented here may be significant as test results will be more easily available, and this will be monitored using this study as a baseline.
This may be significant, especially given that up to the peak of lactation, reduced feed intake is usually observed in cows.
Overall, the influence of UA on the circadian rhythms of the intestinal barrier holds not only potential for treating IBD, but also may be significant for metabolic diseases caused by modern lifestyle factors such as shift work and social jet lag.
As such, disruptions in MEL concentration may increase oxidative stress burden during pregnancy, which may be significant enough that the fetus incurs some degree of oxidative damage.
Analyses of patterns of morphological variation in Pericallis therefore suggest that past failures to recognise morphologically distinct taxa in the Azores do not appear to be an explanation for the lack of SIEs in Azorean Pericallis even though it may be significant in other groups.
First, there may be significant differences in the neural efficiency level of the participants, hence explaining the lack of significant correlation between performance and HbO2 concentration.
Differences between the seed dispersal phase and the seedling or juvenile phases may be significant, although inbred material is often selected against in these phases.
This suggests that allosteric interactions between the TLDc and other accompanying domains in this family of proteins may be significant.
These results should be confirmed in vivo and may be significant clinically.
Aggregation over 4 min on all Windows Beyond the question of how long it typically takes to collect the 48 windows, we need to understand the impact of the fact that at times there may be significant periods with no valid sound at all.
Alternatively, there may be significant allelic differences between ecotypes in epigenetic machinery genes and their promoters.
The highly nonlinear relationship between tobacco product use and CVD may be significant in assessing the effects of e-cigarettes in which reduction in toxicant exposure has been assumed to lead to proportional reduction in harm.
However, within an RCT, participants usually demonstrate a wide variety of responses, indicating that although the mean effect may be significant, it will be less or not at all effective for some individuals [ 4 ].
The same authors suggested it may be significant that Asp-box motifs reside mostly in secreted proteins, except for cytosolic sialidases and sulfite oxidases.
This suggests that there may be significant subresolution processes occurring which it was not possible to detect.
In addition, the resources consumed to develop, evaluate and renegotiate contracts themselves may be significant [ 5 ].
Thus, while there may be significant differences in surface area between amosite and crocidolite samples, rather large differences exist between the amphiboles chrysotile and erionite, even when considering fibers of comparable dimension.
Quantitatively, factors such as gender, education, marital status, occupational status, perception of the current social environment, and sexual orientation may be significant predictors.
Taken together, this evidence indicates that the deactivation of the RIZ1 tumor suppressor gene may be significant in the progression of esophageal cancer.
Also, we present many comparisons and some p -values may be significant by chance.
Subcutaneous emphysema ( Figure 5-158 ) may be significant in these cases and may be the patient’s presenting complaint.
The additional elaborations (lateral filaments) of the Ochromonas mastigoneme may be significant in in- creasing the effective surface area of these struc- tures.