“may be significant”

Macrophages express hormone receptors [ 13 ] and because of the systemic nature of these metabolic hormones and the significant role that macrophages play in tumour development, the potential of dysregulated hormone levels to modulate tumour microenvironments and hence macrophage inflammatory responses may be significant. 2.

A few studies have investigated predictors of acute lymphopenia after PNI for the treatment of PCa 34 ; they reported that acute lymphopenia may be significant, with typically reported drops up to 20%-30% of the baseline values. 11 , 36 Findings from multi-centric prospective studies on sufficiently large cohorts, however, have never been reported.

Resistance to therapy may result from various factors, and mutations in genes encoding SSRT may be significant, leading to structural changes in receptors.

Based on these observations, we hypothesized that survivin and VEGF may be significant in acute lymphoblastic leukemia.

In Go–No go and Hayling, it may be significant that deficits follow a previous set of trials with a different instruction ( cf .

[13] As such, even if CMT is similar in the third year of treatment, there may be significant differences between visual gains.

This may reflect the fact that deprived communities in Glasgow are even poorer than the most deprived fifth of areas across the country; our study communities were in the most deprived 15% of neighbourhoods at the commencement of our study, indicating that there may be significant differences in the experience of poverty between neighbourhoods, even at the lower end of the deprivation spectrum.

There may be significant variations in the resources available, the protocols followed and the adequacy of staff training, which could influence the results obtained.

This fragmented system can create challenges in clinical trials concerning participant recruitment, diversity, and applicability of findings, as there may be significant differences in access to healthcare services and treatments.

By constructing various truncated forms of PIEZO1 (N‐terminus 1‐730aa, middle domain fragment 731‐1959aa, and C‐terminus 1960‐2520aa), we confirmed that HSPA5 interacted with the C‐terminus of PIEZO1, and may be significant for PIEZO1 regulation (Figure 7J through 7K ).

However, there may be significant regional differences in the preferences.

As this was a secondary analysis of data from a randomised control trial, a power calculation was not performed and hence some findings may be significant if repeated in a large cohort. 4.3.

The present result reminds us that care should be taken when interpreting the population representations found by these methods: in some cases, these representations may be significant indication of collective population codes hidden at the single-neuron level, while in other cases they may be simply a redescription of single-neuron tuning.

This may be significant, as the limbic striatum consists of the nucleus accumbens and the head of the caudate.

24 The channels that hold recumbent membrane potential lead to membrane repolarization, which may be significant for holding uterine silence. 24 Vasak et al. concluded that the PDS peak frequency of contractions which lead to cesarean section was significantly different from contraction in normal vaginal delivery. 23 Fetal head station and cervical dilation are the two main physiological factors by which the progress of labor is evaluated, and uterine contractions affect both factors. 25 It seems that the uterine activity is an adaptation mechanism, in case there is an obstacle during the fetal descent.

produce butyrate, their role in promoting enterocyte turnover and preserving tight barrier junctions may be significant.

Considering the practical implications of satellite-cell pool depletion with age, we identify two cases in which the depleted pool may be significant: (i) when satellite cells are heterogeneous in their ability to produce myogenic progeny and to self-renew; (ii) when each myofiber depends on its own satellite cells.

Abstraction during the dry season by hoteliers may be significant, but there are no available records for abstraction rates in the region.

We chose this specific selection of study groups and blood sampling time-points to demonstrate that, depending on the time-point of the latest performed vaccination, there may be significant differences in equine immune responses.

However, \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$g_{r}$$\end{document} may be significant in the case of rotor failure and is therefore included.

A general approach to achieving much reduced κ values therefore remains elusive and the effects of synthesis and processing may be significant [ 17 , 18 , 19 , 20 ].

Therefore, cell cycle distribution may be significant in developing potential chemotherapy drugs.

Given that a person takes thousands of steps daily, the potential cumulative effect may be significant.

There may be significant differences in RNA expression at different time points or in different tissues at the same time point.

Contact resistance may be significant for these reasons [ 16 , 26 ]: (a) the surfaces in contact are not always flat and smooth, (b) the surfaces in contact are not always ideally clean, and they often contain natural oxide and other surface contaminants, and (c) the contact resistance strongly depends on the force.