“may be significant”

For example, the energetic costs of wound healing may be significant for infected individuals upon emergence from hibernation (Fuller et al. 2011 ) and the decreased availability of social thermoregulation and increased likelihood of roosting solitarily may further increase energetic expenditure (Wilcox and Willis 2016 ).

Since there may be significant variation in medical education globally, the prevalence of knowledge among participants was revisited post-piloting.

Our data highlighted the clinical utility of WHO 2009 in describing non-DHF manifestations of dengue that may be significant, and some areas that can be refined in WHO 2009 dengue classification.

Further research is necessary to investigate this discrepancy, as the nature of the difference may be significant.

Their ability to prevent the accumulation of the inhibitor NH 4 + , likely through assimilation, may be significant when considering the implementation of a bioremediation strategy.

Our data also point out that there may be significant shortcomings in the decision-making processes related to the use of coercion as well.

The mobility condition of the object is difficult to forecast, so there may be significant discrepancies between various periods.

The effects of ethnicity on RTW may be significant, although the reasons may not be clear [ 117 ].

Hence the pattern found in CADH P2 may be significant in determining its allergenicity.

The relationship between neurofilament light (NfL) and BDNF, while underexplored, may be significant in the context of rmTBI.

The role of CYP2D6 in the brain may be significant when the classical route of serotonin synthesis governed by tryptophan hydroxylase 2 (TPH2) is impaired [ 50 , 51 ] and/or when the CYP2D gene is duplicated or amplified ( CYP2D6*2 gene variant) or when CYP2D activity is modified by such inducers as alcohol or nicotine [ 43 , 52 , 53 , 54 , 55 ] or by psychotropic drugs, such as antidepressants [ 56 , 57 , 58 , 59 , 60 ] or neuroleptics [ 56 , 61 , 62 , 63 , 64 ].

We would like to point out that the association with Helicobacter pylori infection, which we observed in our study may be significant.

Although, we were not able to differentiate the effect of full-length E6 and E6 splice isoform on the expression of different RNA populations in our study, our observations likely show the cumulative effect of different E6 isoforms and E7 oncoprotein on RNA expression in our experimental system which may be significant in tumorigenesis.

Notably, a differed HR status was validated as the prognostic significant factor in breast cancer bone metastasis, and the results may be significant for risk stratification in breast cancer bone metastasis and guide tailored treatment.

Furthermore, the results based on the MABC in China, Czech Republic, Italy, Japan and the Netherlands suggest that there may be significant cross-regional differences in motor competence among children, and the results highlight the importance of validating these motor assessments when they are introduced to new regions [ 8 , 9 , 10 , 11 , 12 , 13 ].

It should be noted that for distances at which the effect of the turbines may be significant, the far field criterion is usually not met, as in general [ 11 ] (21) R T x − W T i < 2 L 2 λ where L gives the tower length (m).

This suggests that nicotine’s effect on relieving postoperative pain may be significant after adjusting for publication bias. 3.5.

Mind wandering and dreaming, which we will refer to collectively as spontaneous thoughts and experiences (STE), comprise a substantial part of experience in the vast majority of people, may be significant determinants of wellbeing, and can be altered in a range of ways by neuropathology ( Chen et al. 2019 , O’Callaghan et al. 2019 ).

However, there may be significant health benefits for women to receive timely diagnosis as women who are diagnosed later in life are more likely to attempt suicide [ 14 ].

The contribution of NF-B may be significant in IMQ-induced psoriasis-like inflammation.

There is no guidance as to what other serologic tests to order and when, so there may be significant variation in the extent of the evaluation.

That larvae remain trapped inside a durable and non-permeable cuticle for some time after maternal death may be significant: even when the mother is dead, resources derived from her are protected inside her cuticle from exploitation by non-relatives (including other species).

Accordingly, our result needs to be cautiously interpreted in the setting of a community center and there may be significant disagreements in applying our result to physician-based community, as suggested by Flaherty et al . 25 Sixth, there was substantial heterogeneity in the IPF proportion with possible and inconsistent UIP diagnoses, presumably because the IPF prevalence in each study was different.

This is expected, because under P-limitation P and RNA more directly reflect the non-storage requirements, and P-content is not confounded by excess storage (luxury consumption), which may be significant under nutrient replete conditions ( Klausmeier et al., 2008 ).

For regression models that include all data from all samples (allLR, MER, and CRR), depending on which cell type(s) a DMP affects, both or either of the main effect and interaction term may be significant, so both terms must be considered when assessing these methods.