“may be significant”

Therefore the potential impact of global tubular and tubulointerstitial function loss in CKD may be significant although difficult to differentiate from the concomitant loss of GFR.

64 However, observation of even mild movements in one body area (ie, an AIMS score of 2) in a clinical practice setting may be significant and sufficient for the diagnosis of TD.

Similar experiments have been carried out with P450 isozymes 2E1 and 2B1. The possible occurrence and role of FMO in the nervous system appears to be important not only because TDZ and several of its metabolites have similar biological properties and activation within the target tissue may be significant but also because the FMO has been shown to activitate phosphonates by metabolism to their oxons (43,87,88) and to carry out the sulfoxidation of phorate and other Environmental Health Perspectives * Vol 104, Supplement I * March 1996 102 PESTICIDES AND ENVIRONMENTAL HEALTH insecticides.

These indicators may be used in future work, although there may be significant overlaps between high disease (i.e., cardiovascular or respiratory) and low income population in many cities ( Cardet et al., 2018 ).

Although we classified hospitals based on primary, secondary and tertiary centres for the purposes of analyses, it is noted that there may be significant variations within these categories.

[ 3 – 7 , 10 , 11 , 13 , 17 , 22 ] We should bear in mind that other factors, especially above two factors may be significant depending on the patient landscape and context of the study.

In addition, it found that there may be significant confusion among both voluntary and involuntary patients regarding their legal rights.

The potential uses of this route in synthetic and medicinal chemistry may be significant, since the products share structural and functional group properties of the biologically active molecules.

Conclusion This case report, including a literature review, revealed that careful follow-up may be significant for the early detection of P. multocida infection when the participant with immunocompromised background due to liver disorder, alcohol addiction, diabetes mellitus, and/or history of aortic surgery was harmed, especially was bitten by an animal, in addition to its clear clinicopathological appearance.

These R rs spectra are for illustrative purposes only as the temporal mis-match for any given match-up with the weekly composite image may be significant.

Therefore, when degradable materials are implanted in different tissue parts, there may be significant differences in degradation behavior.

The fact that a weather-based prediction of migraine attacks is not feasible highlights the complexity of the pathophysiology of migraine and supports the assumption that migraine attacks may be the result from a combination of multiple factors, none of which alone may be significant enough to trigger an attack.

These unknown allelochemicals may be significant in explaining the formation and maintenance of Alexandrium blooms through direct destructive effects on competing algae or unicellular grazers [ 13 , 15 – 17 ].

There may be significant clinical or statistical heterogeneity among eligible studies that may not be amenable to meta-analysis.

9 For many women who were unaware of how to utilize pelvic floor muscles appropriately prior to delivery or for women who have had multiple babies without adequate rehabilitation and recovery, there may be significant dysfunction in attempts to self-train these muscles. 2 Recommendations for musculoskeletal intervention postpartum vary from no activity until medical consult to full clearance to self-guided exercise at six weeks, suggesting discussions of varying types of delivery and tearing or injury may not be

2012 ) and, in the case of social species, the implications of introducing new individuals may be significant.

In this study, we did not investigate the role of the potential interaction between the use of screened bottom boards and a particular varroosis treatment method, which may be significant.

Top-layer thickness is a key factor in determination of layered tissue OPs and may be significant for neoplasia detection.

The distinction between resident and circulating innate immune cell populations is becoming increasingly important in understanding key inflammatory mechanisms present in asthma, because recent studies have indicated that there may be significant functional differences in these cell populations ( 16 ).

biochemical markers growth hormone IGF-I therapy treatment response acromegaly Several studies have shown there may be significant improvements in specific comorbidities such as diabetes in patients who have a substantial reduction in IGF-I, even though the IGF-I value remains above the normal range ( 39 , 66 , 68 – 72 ).

87 , 115 However, awareness of toxicity related to off-target effects, such as those on VEGFR (hypertension, hemorrhage, perforation) is also necessary as these may be significant. 115 Additionally, tivantinib appears to have cytotoxic effects that are independent of its MET-inhibitory activity and significant rates of neutropenia and neutropenia-related deaths have been documented with the use of this compound. 100 , 132 Resistance to MET inhibition Acquisition of novel mutations, redundancy in intracellular signaling pathways, and downregulation of inhibitory feedback mechanisms have been demonstrated to be responsible for de novo and acquired resistance to other TKIs, such as those inhibiting EGFR, BRAF and mitogen-activated protein-kinase kinase (MEK).

Our data also suggest that there may be significant differences in opsin gene expression between the sexes.

This finding may be significant in terms of the methods used to control indoor resting populations of An. funestus if the mass killing effect of insecticide application proves increasingly inadequate against blood-feeding females already carrying the insecticide resistance phenotype. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2008 Jun 19; Accepted 2008 Oct 31; Collection date 2008.

The additional regulatory mechanism for SP-B expression revealed here may be significant in vivo with respect to alterations of alveolar epithelial integrity, e.g., by inflammation or ventilation.

It is worth pointing out that, according to the literature, 7 - 11 , 17 - 19 although the gain at the inner dimensions of the nasal cavity after RME procedure may be significant, its use for respiratory purposes only is not justified.