“may be significant”

Although the mechanisms involved were not specifically elucidated in this study, it may be significant in our own experiments that PD-L1 expression by H1-DC was unaffected by rapamycin treatment, being upregulated in response to maturation stimuli, irrespective of prior exposure to the compound.

Soy product consumption and duration of physical exercise may be significant factors influencing psychological symptoms among Tibetan college students in high-altitude regions.

That study demonstrated the importance of considering histopathologically benign variants, as this characteristic may be significant in tumor responsiveness to specific chemotherapeutic agents ( 85 ). 7.

Although these complications may be rare, given the vast number of patients affected worldwide, the cumulative morbidity and mortality from them may be significant.

, ARMS), there may be significant differences regarding operational details (such as resection range, depth, and instruments used) among different studies/centers.

Altogether, however, the results they published so far, further highlight the need to develop suitable cell models for drug testing, by clearly demonstrating that there may be significant differences between the results obtained in vitro in fibroblasts vs. neurons using the exact same therapeutic molecule.

The contribution of other components such as cell walls (dietary fibre), which are not digested, may be significant until the cell wall polysaccharides are fermented in the large intestine. 3.5 Macro- and microstructural characteristics of recovered particles (pellet) Photographs of the sediments of the raw and cooked oats, examined after 72 h incubation and centrifugation to remove the supernatant, are presented in the supplementary material (Fig.

The identification of protein antigenic epitopes aids in the identification of protein areas capable of generating a robust immune response that may be significant for producing antibodies.

Given the dynamics of sea lice infestations within salmon farming areas 10 , and the size of farm populations treated, the selection pressure for drug resistant sea lice may be significant.

Given that cefazolin is a hydrophilic drug, the magnitude of the effect of CPB on cefazolin PK may be significant.

The results may be significant for developing location-specific prediction models using internet query data, providing a foundation for constructing early warning systems using such data.

The results for them may be significant, as the moduli can vary with age [ 26 ].

The downregulation of hormone receptors expression in EC may be significant for invasion and metastasis and, added to the expression of CSCs markers and loss of E-cadherin expression, lead to the hypothesis that CSCs possess the capability of EMT [ 56 ].

Given that there may be significant associations between psychedelic use and use of other substances, the lack of this data serves as an important limitation in understanding the effect of this data.

Here, we characterize the hydro-physical parameters of the deep pools that may be significant to the ecology of river dolphins.

This trend of NNMT expression in OSCC suggests that this protein may be significant in early stages of malignant progression.

Related to this may be significant correlations observed between Google Trends relative search volumes using the words “sunbathing” or “vitamin D” with confirmed COVID-19 cases during the March-April lockdown period (r≤0.668, p < 0.001) ( 71 ).

As such, a threshold between 7–9 hours/day of SB may be significant not only for all-cause and CVD mortality, but also for individual biomarkers of T2D.

The residues in food products of active substances of herbicides used in plant production may be significant risk factors for lipid metabolism disorders, such as increased levels of triglycerides, total cholesterol, and low-density lipoprotein (LDL) fraction; lowering the level of lipoproteins in the blood; blood density (HDL), which leads to an increase in atherosclerotic changes in the aorta and coronary arteries; and diseases of the cardiovascular system.

With regard to the reference experiment, this means that, even if these reactions occur to a low extent during the sorption stage, the effect of the H 2 formed on the purity of the outlet stream may be significant, which explains the considerable outlet flow rate of H 2 during the sorption stages (cf. blue line in S stages in Figure 3 ).

However, it may be significant that there are certain patients among those in Table 1 (#6, #10 and #11), who retain LRG1 expression at moderate or high levels in myofibroblasts.

The phylogenetic importance of crustacean-infecting microsporidia in understanding the origins of species like Enterocytozoon bieneusi that infect humans may be significant.

Table 1 gives that correlation coefficients between NmF 2 /EUV/HLα and monthly Ap in general are low although they may be significant.

This approach was adopted to ensure that the model would effectively capture network dynamics in a cohort where there may be significant between-subject differences in static connectivity (see ( Vidaurre et al., 2021 ) for a summary of different possible approaches to modelling with HMM).

As has been observed in previous stroke rehabilitation dose-response studies, there may be significant dose-response relationships that take effect only within specific subpopulations of stroke survivors not evident when analyzing the cohort as a whole ( Lincoln et al., 1999 ; Parry et al., 1999 ).