“may be significant”

CoQ 0 inhibits expression of c-myc, cyclin D, and survivin in melanoma cells CoQ 0 significantly inhibited the β-catenin in B16F10 cells; it is logical to speculate that down-regulation of β-catenin's transcriptional targets, including c-myc, cyclin D, and survivin, may be significant evidence of CoQ 0 -induced growth inhibition in melanoma cells.

Indeed, the subfraction HbA1c, glycated at the amino-terminal valine residue of the β chain, may be significant with increased level of blood glucose over prolonged periods of time and, for this reason, is considered an important biomolecular marker for evaluating long term control of diabetes.

In optimal osseous settings, the differences of the large IOFix screws may be significant in a sawbone model, however, measurements might not be advantageous in the clinical setting.

2001 ), suppression of MAF/FLC paralogue expression in transgenic plants or the formation of truncated transcripts may be significant impediments to the functional analysis of single MAF clade genes.

The influence of this on findings may be significant, since the clinical course of exudative AMD and GA are quite different ( Stanford et al. 2009 ).

Therefore, EFA was performed and yielded eigenvalues with a pattern in the scree plot that suggested as many as 30 factors may be significant using the threshold criterion of Cattell (1966) [ 28 ].

This may be significant in the context of the Licensing Act (2003) which introduced late night and extended licenses, leading to greater temporal availability across the country, although there is some evidence to suggest that the impact of this legislation on public health and disorder may have been to temporally displace rather than increase alcohol-related harm [ 41 , 42 ].

In the absence of selective isotope labeling, such topological matters are inconsequential to a chemist, but they may be significant to an NMR spectroscopist in the rare cases where the reactants have nonsymmetric nuclear spin states.

While this additional energy may be small (of the order of 1% of the total substorm energy budget), it may be significant, particularly in controlling substorm onset.

It is also crucial to mention that FLCs can be transferred from sera through the impaired blood-brain barrier and a qualitative demonstration of FLCs in the CSF may be significant only in the absence of altered BBB function [ 31 ].

These types of changes may be significant for promoting walking in local neighbourhoods as associations between positive perceptions of the community (including having a strong sense of belonging, feeling safe and considering the community to be harmonious) and levels of walking have previously been observed [ 44 ].

The meta-analysis down-weights TrF-pathway co-expression patterns specific to one data set, even if this pattern may be significant in the data set ( Figure 3A ); and enhances the patterns consistent across data sets but may not be significant in any one data set ( Figure 3B ).

Translational Issues: from Experimental Studies to Clinical Trials The negative results of these recent clinical recovery trials may be significant enough to challenge the whole concept of post-stroke recovery enhancement.

Likewise, it is to be noted that some jarosites show long-range magnetic order implies that further-neighbour interactions may be significant in these materials, stabilising a particular spin configuration relative to the others 60 .

Contribution of the study Our study showed that the patients’ dietary habits, eosinophilia, and markedly elevated IgE levels may be significant predictors for the physicians to suspect fascioliasis. 9 3 2020 55 1 67 67–71 30 3 2020 Copyright: © 2020 Turkish Archives of Pediatrics This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License Abstract Fascioliasis is a trematode flatworm infection caused by Fasciola hepatica and F. gigantica.

Even though the presence of granular cells in ameloblastoma is infrequent, the observation that it accounts for so many cases of malignant disease may be significant.

For example, in patients with volume depletion or renal artery stenosis, the decrease in GFR may be significant [ 41 ].

Early intervention against “sadness,” “failure,” and “unimportant” may be significant in suicide prevention clinically.

Food resource quality (δ 15 N) and morphological shape, especially body and wing size, may be significant factors that directly or indirectly affect the gut bacterial community of carabid beetles.

Therefore, it is expected that there may be significant differences in the intermediates produced during the two processes.

However, cholecalciferol supplementation in dialysis patients causes an increase in both 25(OH)D and 1,25(OH)2D levels, suggesting that extra-renal activity may be significant in these patients [ 14 ].

However, it may be significant that overall, bull elephants in Thailand appear to be in better physical and physiological health compared to females at the same camps.

Thus, personality characteristics may be significant predictors of PTSD symptoms and negative emotions in disaster survivors.

pombe may be significant in this connection (Additional file 1 : Figure S1C).

Since there may be significant background noise which may cause some bias to the results, we perform the analysis by correcting for the ChIP-seq input data.