Barely Significant
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“may be significant”

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In the literature

36 The lung is a common site for the metastasis of lymphoma; clinical signs may include marked pulmonary edema or effusion, which may be significant enough to mask the radiologic signs associated with a disseminated tumor.
Neoplasia
Ferrets, Rabbits, and Rodents · 2011 · PMC7158188
The estimated carrier frequency of FMO3 pathogenic variants in a British Caucasian population is 0.5% to 1% although there may be significant variation in carrier status in different ethnic groups. 4 , 14 To date, the genetic profile of the Irish individuals affected with TMAU and the severity of their clinical expression has not been studied.