Barely Significant
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“may be significant”

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In the literature

The differences in chemical structures between SPX-C and D, that present an additional methyl substitution on the imine ring, and SPX-A and B may be significant, as the first two compounds are resistant to oxalic hydrolysis whereas the second two compounds are converted to the biologically inactive SPX-E and F when the same reaction is applied [ 3 , 20 , 21 ].
25 We estimate that quantum tunneling due to the coupling of the 4f magnetic moment with the nuclear spin may be significant only for selected values of the magnetic field, in the range B ≲ 40 mT, thus it cannot explain the field dependence of τ in our investigated field range (see Figure S8b of the Supporting Information for the effect of the coupling between 4f moment and nuclear spin in the field range of the experiment).
Previous research has suggested that, e.g., the role of the type of medications used to relieve withdrawal symptoms may be significant with regard to detoxification treatment retention, specifically among individuals with opioid use disorder ( Backmund et al., 2001 ; McCambridge et al., 2007 ) and analysing the impact of medications used on treatment completion also warrants further attention in the Finnish context.
Information obtained from whole-tract analyses are limited because there may be significant variations in diffusion characteristics along the length of white matter tracts ( Johnson et al., 2013 ), and it is likely that some pathological tract alterations occur in circumscribed regions within tracts and not along entire tracts in patients with TLE.
Although the demands and challenges of COVID-19 have demonstrated that there may be significant shifts in support and funding that make resources and attention relatively scarce at institutional, state, and governmental levels, our findings demonstrate that important perinatal quality goals may be meaningfully achieved, particularly concerning topics and measures central to the prevention of SMM and maternal mortality, such as severe hypertension in pregnancy and the postpartum period.