“may be significant”

Intriguingly, SUMO-1 is conjugated to K6 and K9 equivalently in the absence of other modifications, whereas phosphomimetic substitutions of S13 and S16 appear to block SUMO modification on K9 or promote SUMO-1 modification on K6, which may be significant to regulation of other HTT modifications, such as K9 acetylation.

Owing to a more restricted expression pattern of IFN-λ4 compared with IFN-λ3, rs4803217 effect on IFNL3 stability may be significant enough in those conditions when IFN-λ4 is not expressed.

Although the concentrations for both the 4,4′ and 2.4′-MDI species were low, and other MDI species were not detected, moving forward with future testing and analysis of other isocyanates such as HDI and TDI, these findings may be significant for several reasons.

However, a new diagnosis and being physically active at baseline, and higher levels of education, exercise self-efficacy, and motivation may be significant predictors of frequent program attendance in CHF patients 15 , 16 .

Yet, the children may be significant in giving meaning to life (Mueser & Fox, 2002 ; Trulsson & Hedin, 2004 ).

According to the available epidemiological data, there may be significant differences in serum prevalence among different populations.

Differential linkage disequilibrium of variants with TLR5 1846T>C across populations In light of the evidence in favour of selection for TLR5 1846T>C in Yorubans 19 , but our inability to conclusively determine a clinical effect of TLR5 1846T>C independent of TLR5 1174C>T in Thais, we hypothesized that there may be significant population-level differences in LD structure in TLR5 .

An additional complication is that temperature seasonality may be significant in northern Thailand (north of c.18° N), where cooler winters reduce dry-season water stress and extreme low temperatures at high altitudes may exceed physiological tolerances.

This dual tracking of stated preferences and observed patterns recognizes that there may be significant variation between how people think they ought to make decisions and how they actually process information and arrive at choices most effectively.

Since the time kinetics of skin and vascular manifestation, and viremia probably vary among different infections, it may be significant to measure blood viral load at different time points (before, during, or after lesions onset), thereby determine the appropriate time of biopsies for molecular identification. 5.

Regular dental check-ups are important, not only to monitor dental health, but to also increase the likelihood that some systemic diseases - some of which may be significant - are diagnosed at earlier stages. status released display-pdf yes is-in-collection-domain yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2025 Jan 26; Revised 2025 Apr 25; Accepted 2025 May 1; Issue date 2025.

The non-significance of demographic factors suggests that structural (curriculum design, for instance) rather than individual factors may be significant determinants of academic performance and referrals.

Further personality traits that may be significant for enhanced understanding of binge-watching are sensation-seeking [ 34 ].

This may be significant, because visitation to small pocket parks, which were closed in many cities during the pandemic, were not captured in our data.

The FDG-avid pelvic lymph nodes may be significant for lymphatic spread of the cancer to the skeletal muscle.

Moreover, it may be significant that the entropy generation rate S ̇ therm is independent of the degradation mechanism, as long as only S config and S ̇ therm are involved in the degradation process due to R 2 , but it deserves further investigation. 4.

They found that MIKCC genes may be significant for regulating the floral organ development in I. trifida ( Zhu et al., 2020 ).

HDAC6 may be significant.

Given the fact that vitamin D is generally deficient and metabolically disordered in patients with CKD [8] , [9] , supplementation of vitamin D may be significant throughout CKD evolution, especially at early and moderate stages.

There may be significant variations between studies due to sample size, follow-up time, age and dose.

These results suggest that the increased proportion and stronger immune-suppressive function of Tregs in ODSCC may be significant factors contributing to the more severe TISME in ODSCC.

The framing effect may be significant, yet most participants who encountered the negative frame would not have responded as predicted by prospect theory ( Kahneman and Tversky, 1979 ) or other theories of framing, such as the explicated valence account ( Tombu and Mandel, 2015 ; also Wallin et al., 2016 ) or the fuzzy trace account ( Reyna and Brainerd, 1991 ), all of which make the same predictions for the standard ADP (but which diverge in prediction as well as explanation under other task conditions).

This statement is particularly true for short half-life diagnostic radiopharmaceuticals such as 18 F and 99m Tc, where the impact of clock offset on the final relative standard uncertainty may be significant (see also Figure 1 ).

Because employees spend much of their time at work, their WSE and its influence on health may be significant.

Unfortunately, communication among these groups is not always frequent or timely, suggesting that there may be significant professional, structural and institutional barriers to adopting the widespread use of sentinel events to protect human health [ 110 ].