“may be significant”

The residue R113, located at the edge of a α-helix of the casposase monomer, forms a hydrogen bond with D110 from the other monomer, which may be significant for the tetramerization of casposase.

We plan to study this problem in the future, referring to some application contexts where discriminating among different stages, associated to different populations, may be significant.

However, this method also has inevitable shortcomings, as there may be significant differences in the economic fundamentals behind stocks that have reached limits and those that are about to reach limits, and even if the stock has not reached the limits, its price trend may still be affected by the limits [ 4 , 13 ].

However, the use of health information technology and other factors such as health literacy may be significant barriers to actually engage older adults.

Younger age, a lower dose of insulin, and a higher baseline postprandial glucose level may be significant predictors of successful switching from insulin to GLP-1 receptor agonist therapy.

Importantly, there may be significant selection bias in the children who were tested based on the indication for obtaining the tests, availability of tests, and access to testing locations and hence the eventual inclusion of the children in the study population.

Natural sources of desthiobiotin Retaining a single gene of a pathway, as in the case of bioB , may be significant only if the respective required vitamer, desthiobiotin, is available as public good in marine ecosystems.

Immunosuppression regimens and a prevalence of cardiovascular disease risk factors in the post-LT patient population may be significant contributors to the increased risk of cerebrovascular disease in LT recipients.

Our study has some notable practical implications, which may be significant to mental health promotion in adolescents.

Restrictions on seeing family members and friends and participating in sports and recreational activities may be significant contributors to reduced psychological wellbeing.

VE-Cadherin, CD31, and CD146 are typically associated with a more mature endothelial phenotype; however we showed that LO-EPC had a higher level of VE-Cadherin compared to mature endothelial cells (HAEC), which may be significant in ensuring that LO-EPC resist tractive flow forces.

Side effects may be significant especially with long term administration and include hypothyroidism, skin photosensitivity, chemical hepatitis, pulmonary fibrosis and corneal microdeposits that are reversible.

Modeling of the protein also suggests that there may be significant size and/or shape constraints on the structure of the hydroxamic acids.

It is suggested here that these factors may be significant contributors to the TMS effects described above, including the long-lasting effects.

Additionally, the study did not differentiate between men diagnosed in childhood versus adulthood, which may be significant as literature suggests those diagnosed in childhood may experience more severe impairments if symptoms persist into adulthood.

This implies that PRDX1 mutations may be significant in the onset and progression of gastrointestinal cancers.

Therefore, we cannot exclude that the effect of output current on laryngeal muscle, which is one of the putative mechanisms of VNS‐induced SBD, has already decreased with chronic stimulation, although it may be significant in acute stimulation.

Bee colony metrics of adult bee mass and brood surface area, and measurements of bee head weight, newly-emerged bee weight, and hypopharyngeal gland size were not significantly affected by methoxyfenozide exposure, suggesting that there may be significant effects on honey bee colony behavior and health in the field that are difficult to detect using standard methods for assessing bee colonies and individuals.

Furthermore, a follow-up study, including those with and without POAG, to track changes of ONH-RNFL thickness over time may be significant and allow changes to be detected at an early stage.

There may be significant differences in the degree of brain insulin resistance in a given individual, as is observed in the periphery.

The influence of the joint phosphorous contribution of piscivorous and herbivorous water birds may be significant (up to 6.6% of P at the outflow) on the often phosphorous-limited wetland nutrient loads, while the nitrogen contribution dominated by herbivorous geese is limited (up to 0.7% of N at the outflow) in the case of Dumbrăvița.

In addition, some factors may be significant in one model but not in the other.

However, genetic variability, environmental influences, crop management, and abiotic/biotic stresses can all cause significant variation in grain composition, and variation among sorghum germplasm may be significant due to the rich genetic diversity of germplasm [ 12 ].

This for sure indicates that MSC-EXOs could inhibit the NF-κB pathway, which may be significant during the inflammation development in IRI [ 44 , 57 , 58 ].

Sigma factor balance That both of these mutants directly affect the level of sigma factors within the cell may be significant in explaining the general mechanism by which an alteration in growth rates and death frequencies is achieved.