“may be significant”

ed to 3′‐untranslated region binding (CPEB4, hnRNP‐A1, and TIA1) and transcript stability; (5) there appears to be a difference in how AS is regulated by aging, with older individuals having high RBP expression and more splicing changes; and (6) our mouse LRS data revealed that more splicing events may be significant 24 h postexercise, compared to transcriptional events being highly enriched at earlier time points.

Irrespective of any selection bias, the size of the difference between the observed fall incidence rate of 69% for the entire sample and a rate of 35% suggests that there may be significant under‐reporting of falls, either due to definitions that exclude certain falls or due to incomplete data capture. 5 CONCLUSIONS This study demonstrates that the trade‐off between data accuracy and participant attrition found in earlier fall studies may be a function of the method of data capture and is not inevitable.

Consequently, the RCS presented by such an antenna to a threat radar may be significant.

Other studies have shown that underreporting may be significant and more frequent among groups for which suicide is culturally unacceptable, or it may be higher for women who die by drowning or poisoning, or in general from accidents or violent deaths for which intentionality cannot be established [ 60 , 75 ].

It is important to emphasize that while not all obese individuals exhibit a pronounced proinflammatory state, long-term nutritional deficiencies such as inadequate magnesium intake may be significant factors triggering metabolic abnormalities.

This method also does not account for sequence-specific effects, which may be significant in high-density tiling arrays, and also does not normalize the variance of M .

In conditions of malnutrition, such as cancer cachexia and anorexia, there may be significant alterations in the production of many proteins, such as leptin, secreted from adipocytes with important metabolic and regulatory implications ( 45 ).

In addition, residents and foreign tourists have been exposed to different cultures and educations, so there may be significant differences in behaviour or dressing.

Studies from healthcare services and the general population suggest that absenteeism rates may be significant when fear of becoming infected with novel agents is high, ranging respectively from ∼35 % to 55 % ( Chafee, 2009 ) and from 50 % to 80 % ( Teh et al., 2012 ).

The duration may be significant enough for some changes to occur in the pathological features including the degree of hepatic steatosis, degree of inflammation and to a lesser extent stage of fibrosis to occur and potentially affect the correlation analysis.

Thus, there may be significant advantage in treatment of arterial stiffness to alleviate arterial hypertension.

The major disadvantage of octreotide use is hyperglycemia and decompensation of diabetes mellitus, which may be significant but reversible. 9 In the present, study although 71% of patients experienced hyperglycemia, this was not of clinical significance and none of the patients discontinued the therapy due to this side effect.

However, if HQ ≥ 1, the risk of exposure to BPA through doogh consumption may be significant, and this issue requires further evaluation to ensure consumer health 27 .

1 6 The opportunity cost of investing in DHTs may be significant, and it is essential to ensure they deliver expected benefits and value for money. 9 For conventional healthcare interventions, HTA has been instrumental in generating robust scientific evidence on their effectiveness and cost-effectiveness, as well as examining the organisational, ethical, legal and social implications of their adoption.

These findings may be significant for understanding crop varietal improvement and plant evolution as epigenetic variations, which are induced by environmental stresses, could be inheritable and consequential to adaption and evolution in plants [ 13 , 25 , 59 , 69 - 72 ].

Additionally, there may be significant inter-individual variations in gut microbial composition and hepatic metabolic capacity, which could introduce greater variability in outcomes when TMA or TMAO is measured independently.

Subgenomic differentiation in Brassica may be significant in creating novel types in Brassica species that could help broaden the genetic diversity or increase heterosis.

There may be significant scope for controlling rates of reactions or even positions of equilibrium with sufficiently intense action fields such as laser beams.

Since a substitution from lysine to glutamate changes the amino acid charge from positive to negative, the effect on protein folding may be significant and may change the catalytic activity of the enzyme.

Although small, these differences in sleep characteristics may be significant in light of the fact that the Ts1Cje mice do not show deficits in novel object memory ( Fernandez and Garner, 2007 ).

Clinical investigations have revealed that the potential of AAT is limited when used as a single therapeutic modality, but the therapeutic benefit may be significant when AAT is used in combination with conventional chemotherapy or radiation therapy [3] .

Also, there may be significant differences in the doses and the duration of immunosuppressants, the content of which were not included in the analysis.

However, postoperative adverse effects of liver transplantation may be significant.

Further, previous research suggests that there may be significant individual variations in how self-concept changes during this developmental period [ 48 ].

In this context, the concept of stress-prone, or Type D, personality may be significant.