“may be significant”

Mechanically Induced Nuclear Deformation Activates Oncogenic Signaling and Increases DNA Damage Intriguing recent data have shown that compression and deformation of the nucleus may be significant components of mechanotransduction.

However, two recent studies using very high levels of long chain omega-3 PUFAs suggest that the plasma fatty acid abnormalities can be reversed and that there may be significant impact on behavioural parameters [ 24 , 25 ].

9 What possible cause could an average citizen have to obtain an assault weapon? All perpetrators of domestic violence do not escalate to mass shootings, but the connection between access to guns, mass shooting, and domestic violence may be significant, because for many intimate partner homicides, if a gun had not been readily available, lethal violence would likely not have occurred.

On the other hand, the observation of the S* state in the excited-state dynamics may be significant for the OCP reaction mechanism.

The increased intron number in ancient EpPAL genes may be significant, as intron-gain events can enhance mRNA stability or harbor regulatory elements without disrupting the coding frame of genes [ 25 , 26 – 28 ].

There may be significant hidden blood loss due to bleeding into the tissues and residual blood in the joint [ 16 ].

4 , 5 A full electronic health record might provide more information explaining these differences, and a meta-analysis of previous studies suggests that there may be significant differences in efficacy across these medications. 21 Consistent with previous studies, the average cost per patient over the observation period was lowest in the cohort with the longest duration of monotherapy.

However, in practice there may be significant inertia preventing such optimization, when it requires widespread changes in behaviour or the way shared stereotype groups are defined, for example.

Introduction Bacteremia is recognized to be a serious condition in children, when appropriate investigation to guide prompt management is deemed once morbidity and mortality may be significant when the patient is not treated appropriately ( 1 ).

Several independent predictors of non-diagnostic CCTA revealed in our analysis may be significant, in part, due to their association with high coronary artery calcification (CAC), which is known to impair the diagnostic accuracy of CCTA. 15 , 29 For example, a higher CAC is more likely in patients who are older, diabetic, or hypertensive, 30–32 all of which were predictors retained in one or both of our final models.

The potential implications of lifestyle behaviors on hypertension management and resilience may be significant and is worthwhile for future studies to investigate these associations.

This acidifying action may be significant and long lasting, and is therefore the basis for chronic disease; (c) The degranulation of mast cells and basophils, caused by the stimulus, the basis of the acute allergic response [ 77 , 78 , 80 , 84 , 138 ], as described above in Figure 1 .

35 Therefore, enrichment of ribosomal proteins may be significant to the mobilization of lipids from lipid droplets during TB infection.

In this regard, it may be significant that wild-type NUT and BRDT, a family member of BRD4, are coexpressed in post-meiotic spermatids ( Haack et al. 2009 ; Goudarzi et al. 2014 ).

Clinical manifestations include fever, rapid growth of lymph nodes, and labs may be significant for sudden and severe LDH elevation [ 2 , 5 ].

Insensible losses leading to hypovolemia and kidney injury, through an increased work of breathing, pyrexia, and gastrointestinal manifestations of infection may be significant in individuals with COVID-19.

Therefore, the risk of a dramatic outcome in this patient category may be significant.

This effect may be significant in organic layers with asymmetric molecules or configurations.

The fact that they appear much more regularly around hypertrophic chondrocytes may be significant as to the origins of their formation.

Interestingly, one can quench phase VII down to room temperature, suggesting that the rate of heating may be significant.

In presence of giant CAAs, there may be significant flow alteration.

In this regard, it may be significant that Carmeliet (1961) and Dudel et al.

We observed that the increase in gamasid ticks from July to September coincides with the peak of tularemia epizootics among common voles, and suggests that the role of gamasid ticks in maintaining tularemia epizootics may be significant.

Second, given the importance of joint attention and serve-and-return responding to language development (e.g., Tomasello and Farrar, 1986 ), it may be significant that some types of media are themselves interactive.

While we do not have district-level information about hourly diurnal cycles of fire activities due to a lack of comprehensive in-field studies, our broad conclusion is that there may be significant benefits yielded by encouraging fires to be set earlier (10:00–13:00 LT) in the day rather than later (14:00–17:00 LT).