Particularly for therapeutic applications in vivo, where endogenous anti-AAV antibodies frequently compromise the therapeutic efficacy of gene delivery, the latter characteristic may be significant [ 30 , 114 , 115 ].
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In the literature
The fact that GmAOX1 has higher specific activity and requires less pyruvate for its activation, compared to its more highly expressed AOX2 counterparts in soybean, may be significant in planta because AOX1 is the most stress-inducible isoform in legumes ( Sweetman et al., 2019a ).
Also, while the sequence of the D-stem seems unimportant for serylation, the length may be significant within the context of the particular tRNA frame.
The role of environmental conjugation may be significant in the increase in conjugation identified with age as the transit time in the gut and volume of defecation varies with the age of nematodes ( Portal-Celhay et al., 2013 ).
For beetroot crisps the amino acid glutamine may be significant in acrylamide formation and supports findings of Elmore et al.
Studies on other mosquitoes, especially those of interspecific competition among larvae of similar species, suggest that there may be significant differences in the ecology, physiology, and behavior of even congeneric mosquito larvae as compared to A . aegypti .
For membranes like Purilogics PurexaTM PrA and Cytiva HiTrapTM Fibro PrismA with high dead volume, feed dilution at the inlet may be significant enough to lower the feed concentration into the linear region of Langmuir isotherm.
Quadratic terms and interaction terms were assessed if there were biological or practical reasons to believe they may be significant.
Although the exact meaning and mechanism of the influence of anti-inflammatory cytokines on the development of manic symptoms has not been studied, this similarity between SARS-CoV-2 and BD may be significant.
The benefits of the above approach may be significant.
Cluster analysis was successfully used to classify LULC and determine the LST groups of distinct populations that may be significant in the land degradation for the obtained results of enhanced satellite data of 1984 and 2018.
This may be significant because, after T187 phosphorylation of CDKN1B/p27 KIP1 by CDK2, CKS1B mediates interaction between CDKN1B/p27 KIP1 and SKP2, leading to proteosomal degradation of CDKN1B/p27 KIP1 in the nucleus. 51 , 52 Indeed, in a remarkable feat of drug development, small-molecule inhibitors that target a pocket
This result may be significant because FIV, unlike HIV-1, does not require NUP358 for infection.
Perhaps most importantly, for databases that rely upon administrative coding, there may be significant limitations in data quality.
The variation in communication across the country may be significant in the effectiveness of the message and may lead to disparities in knowledge, understanding, and reactions to the information.
There may be significant numbers of cases who present to health practitioners in the community and are not investigated or are not sufficiently unwell to seek medical attention.
That adhesion to the ECM may be significant is supported by studies by Bezie et al.
Although individual events only occurred with relative infrequency (< 2% of total reads), their impact on pathogenesis may be significant especially given RUNX2 haplodeficiency is sufficient to cause cleidocranial dysplasia [ 47 ].
There may be significant ionic current components present in Ucn3 + and NPY + neurons that are not currently included in our neuron models.
It can be assumed that psychological processes may be significant factors for chronification of dizziness and vertigo ( Tschan et al., 2011 ), so that the selection of patients for our vestibular rehabilitation program may probably increase the proportion of patients with behavioral complications.
These valuable properties of GLM also delayed OA development, suggesting that the effects may be significant throughout the various stages of disease.
The effects of this may be significant in some years in the Beaufort Sea (Kelly et al. 2010 ; Smith 1987 ; Smith et al. 1991 ), but the timing and causes of surges in fox populations are not well understood.
The restricted expression of PIP4Kγ in the CNS may be significant within the context of the specialized function of different neurons.
• The isotropic hyperfine coupling interaction ( H a iso ) responsible for the contact contribution, which may be significant for transition metal complexes ( i.e.
In patients whose history taken in an emergency situation fails to reveal the circumstances and time of dabigatran intake, external sources of information (statements of relatives etc.) may be significant.