Barely Significant
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“may be significant”

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In the literature

Alu sequences have also been reported as having an increased fraction of SNPs [ 57 ], both in the GC-rich body, but also in the GC-poor tail of the Alu sequences, possibly related to increased recombination rates, thus underlining the possibility that AT replication slippage may be significant in the generation of SNPs in the AT-rich tail of the Alu sequence, as suggested previously [ 57 ].
The human genomic melting map.
PLoS Comput Biol · 2007 · PMC1868775
This study illustrates the difficulty in analyzing rare genetic variants: Although there may be significant associations when considered in aggregate (i.e., gene-based burden testing), there are often too few individuals with each variant to test individually with sufficient power.
Alpha-1 Antitrypsin Mutations: Is One Too Many?
Am J Respir Crit Care Med · 2020 · PMC7047447
Conclusions Our analyses indicate that the public health impacts of congestion may be significant enough in magnitude, at least in some urban areas, to be considered in future evaluations of the benefits of policies to mitigate congestion. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-p
Given that final infarct volume strongly impacts neurological outcomes, 2 rescuing penumbral tissue after reperfusion can have major clinical relevance, considering there may be significant secondary injury accumulating over hours, days and weeks. 3 In clinical stroke studies, the measurement of the hyperintense lesion on T2 FLAIR has been conventionally considered as a convenient marker of the final stroke volume at both 30- and 90-days post stroke. 1 However, if the aim is to take a