Barely Significant
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“may be significant”

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In the literature

This shift in responsibility may be significant, as limited survey data reported that most adolescents (68%) relied on parents and guardians to remind them to carry their SIEs. 10 Those with self-described “overprotective mothers” were more likely to fall in a lower behavioral risk group, noted in the study to be the group significantly more likely to carry their SIE, ask about allergenic ingredients when eating out, and avoid other high-risk behaviors. 10 Disclosure of allergy status in a new environment is an issue of concern.
Food allergies on a college campus.
Ann Allergy Asthma Immunol · 2024 · PMC11759065
Limitations The limitations of this study include: (1) As a population-based analysis, we need to be very vigilant against ecological fallacies, and when explaining the results, we can only put forward the scientific hypothesis of the causality of the epidemic trend based on the existing data and previous literature rather than subjectively infer it; (2) There may be great discrepancies in the incidence among different pathological types of TC, which is not reflected in the GBD database; (3) There may be significant differences in incidence rate among different regions of the same country, especially in countries with a large population and a vast territory.
The observation that increased tissue specificity is associated with cancer progression may be significant in view of previously reported divergence in mutational landscape of cancer evolution, from an initial set of common mutations in driver genes to rare mutations in a broad spectrum of genes at late stages of cancer development ( Gerstung et al., 2020 ).
The difficulty with so sim- ple a view is that since we have more apparently mono-cis retinenes than the simple theory encompasses, a new theory may be needed; and this could in- volve new considerations which affect the height of the cis peak. It may be significant, particularly in association with other characteristics to be discussed below, that in the ultraviolet the isoretinenes have a some- what different type of spectrum from the other isomers.
Geometrical isomers of retinene.
J Gen Physiol · 1953 · PMC2147351