“may be significant”

Discussion Recent investigations have demonstrated that systemic inflammation and metabolic dysregulation may be significant contributing factors in the pathophysiological mechanisms of AVF maturation failure [ 6 ].

These include cases where sampling error may be significant ( \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$n = 300$$\end{document} n = 300 ), and when short branc

(Three instruments were equipped with a 675 nm laser, as opposed to the currently used 655 nm laser, which causes only a ≈0.28% calculated difference in the value of dn/dc , based on [ 40 ], which was neglected in the consideration of signal magnitudes.) Thus, an instrument-dependent error of at least ≈3–4% in concentration should be considered when determining protein concentrations based on an assumed refractive index increment and given fringe shift data (in addition to variations in the protein refractive index increments, which may be significant especially for smaller proteins [ 41 ]).

Finally, two cases in which this effect may be significant are: (1) if the structure is undergoing a transient perturbation, e.g. the triangle perturbation of Fig. 2 , in which case measurements of the perturbation timescale cannot be completely relied upon to determine Ω ref ; and (2) if the structure nominally undergoes sinusoid motion but then this waveform is altered, e.g. an insect flight motor during an extreme manoeuvre (see Gau et al., 2021) .

Such levels of extra costs may be important, thus there may be significant selection against the use of the time-compensated sunset compass during spring migration as well as against the use of a fixed sunset compass in both seasons for populations with a NW/SE axis.

Each of these conditions may be significant for different reasons.

The ratio miR-221 : miR-375 may be significant in discerning malignant HNSCC from normal tissue [ 5 ]. miR-205 has been associated with lymph node metastases [ 5 ].

Several series have revealed relatively low operative mortality and rebleeding in the acute setting; however, risk of later haemorrhage from gastric or recurrent esophageal varices may be significant [ 4 , 6 , 16 , 20 , 23 , 24 ].

This section explores several factors which may be significant in this framework for understanding the autism–FND association.

Considering the crucial role of PRMT1 in acute myeloid leukemia (AML) with various gene mutations—including RBM15-MKL1, FLT3-ITD, MLL-EEN, and AML1-ETO fusions—as well as mutations in splicing factor ( Fong et al., 2019 ), PRMT1-mediated metabolic reprogramming may be significant for the previously mentioned AML.

The air quality impacts of MCB may be significant, as decreases in surface ozone concentrations are as high as 21–34% in the tropics, with potential implications for coastal cities.

As azithromycin intracellular concentration was not measured, it would benefit future studies to assess whether this interaction may potentially affect intracellular concentrations, such as within lysosomes or white blood cells, which may be significant given the unique pharmacokinetic characteristics of azithromycin.

Based on the theory of structure-activity relationship, it may be significant to explore biological, functional or pharmacological implications of these communities with respect to herbal combination in further experimental studies.

In particular, there may be significant differences in therapeutic response recorded between xenograft studies that use immunocompromised mice and studies using murine mammary carcinoma models in immunocompetent mice.

It is not known whether this effect is influenced by the processing style, and there may be significant differences between bottom-up and top-down processing.

Their effect on the RBC count, if present, is generally clinically insignificant, and their effect on the WBC count may be significant in some cases.

Given that transformed cells adjust the relative ratio and contribution of de novo lipogenesis and fatty acid uptake based on the availability of different lipid species extracellularly, there is a biologic rationale to postulate that LPL and CD36 may be significant protagonists at the intersection between dietary lipid composition and PCa biology ( Figure 1 ).

Whatever the origin of ghost tags, their accumulation on the research site may be significant and results in difficulties for antenna deployment or in hindered data acquisition by passive telemetry systems.

[ 18 ] Renal tubular metabolic reprogramming may be significant in response to hypoxia, ischemia, sepsis, or other insults because it may reduce energy expenditure and prevent cell death at the expense of non-essential functions.

The roles of C3a and C5a may be significant in the pathogenesis of Fabry disease.

This may be significant for several reasons.

Interestingly, films with 6 wt% LBG and those with7 wt% of the other three additives, not only break at a magnitude higher elongation but are also as strong or stronger than pure CNC films, which may be significant for applications that require toughness.

While more work is needed to explore the economic implications of peer-network technologies for supporting clinical decisions, our findings suggest that there may be significant economic benefits of leveraging peer-network strategies to reduce both medical bias and patient mistreatment.

Microscopic observations also confirm that the type of phase change material used influences the morphology and degree of development of the microstructure of geopolymer foams, which may be significant for their performance properties. 4.

Our study illustrates that gender identity may be significant as a variable even in situations where the data do not support the predictions of gender-identity theory.