Barely Significant
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“may be significant”

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In the literature

Differences in dynamic imbalance between NTG and high-tension POAG There may be significant differences in the characteristics of dynamic imbalance between NTG and high-tension POAG, which may in turn contribute to the differences in their clinical phenotypes: NTG: The static TLCPD remains normal, but the mismatched superposition of IOP peaks and CSFP troughs results in elevated transient peak TLCPD with a relatively low fluctuation frequency.
Significance of observed differences in specific lipids and metabolites Phospholipids Insofar as linoleic acid (18.2) can be converted to longer-chain fatty acids including the pro-inflammatory eicosanoid arachidonic acid (20:4) [ 36 ], the observed increase in phospholipids containing linoleic acid tails in plasma of SAMS patients may be significant.
This finding may be significant in clinical practice, if proven by further research, those in younger age groups, considering their higher rates of metastasis to the brain, may require specific metastasis work-ups such as brain MRI and brain CT to rule-out metastasis to the brain which may be different from older individuals.