“may be significant”

The financial consequences of poor recruitment tend to be overlooked but may be significant, both directly, by the need to extend study recruitment periods, and indirectly, by research waste and the societal costs associated with the production of poor research [ 10 ].

In short, NE differentiation characterizes a multidrug-resistant phenotype in common PCa, and may be significant in at least 10% of PCa patients.

Thus, better returns may not be observed in the short term but may be significant in the long run.

Additionally, a family history of hypertension, insufficient sleep, and shift work patterns may be significant risk factors for hypertension.

The variations in determining the chronological age may be significant [ 1 , 2 ] as they can be as high as 36 months [ 3 ].

These findings indicate that the role of gut microbiota in the development and progression of neurodegenerative diseases may be significant.

This may be significant as inflammatory response changes with the ageing process [ 31 ].

Combined overexpression of miR-200a and miR-200c reduces demyelination in Angiostrongylus cantonensis -infected mice Given the aforementioned results showing that miR-200a and miR-200c may be significant in AC infection, we next asked whether they exert their effects separately or synergistically. miR-200a and miR-200c were administered to AC-infected mice at 7 dpi to maintain high expression levels of both miRNAs in the mouse brain ( Figure 2A ).

Neuroactive compounds produced by probiotics may be significant to cognitive health, including serotonin, GABA, histamine, arachidonic acid, and adrenaline ( Ma et al., 2020 ).

It should be noted that a trend lower than the effect size may be significant in a single data set (Sb, As), but the chance to detect this trend in all possible trials, with samples of the same size and variance, from the same population, would be less than 80%, i.e., the statistical power will be less than 80%.

Structurally, A789V may be significant due to its position near the catalytic motif C as well as the residue D700 in the motif A, however the overall protein structure suggests that all the mutations together may play a role in modifying the active site and facilitating nucleoside discrimination [160] , [161] .

These additional costs may be significant, but from the available literature, it is not clear if such costs were considered due to the lack of care cycle definitions.

The genes involved in both biological processes may be significant.

We hypothesized that there may be significant differences in some genetic polymorphisms between the two ethnic groups [ 40 - 44 ].

For example, the diurnal and seasonal variability of MP levels under every scenario may be significant factors in MP exposure.

Moreover, milk producers who want to buy semen should be aware of the various companies that sell and perform insemination, as there may be significant price differences between them.

Conclusion In Korean subjects with normal spirometry and visually normal chest CT, there may be significant differences in QCT parameters according to sex, age, and smoking history.

multilocularis in definitive hosts [ 13 ], and our data suggest that such a dilution effect ( sensu [ 13 ]) may be significant in summer but absent in winter, when only competent intermediate host species are consumed ( Fig. 2B ).

These results highlight that family-level processes such as the coparenting relationship may be significant relational contexts for the socioemotional development of adolescents.

Therefore, we can infer that spermidine-related metabolic pathways (arginine and proline metabolism, β-alanine metabolism, cysteine and methionine metabolism, glutathione metabolism, glycine, serine, and threonine metabolism) may be significant factors leading to post-weaning piglet diarrhea.

Even if the relationship between Bas1 and the cell cycle is not clear ( 54 ), it may be significant to prepare the cells for division via the regulation of nucleotide and histidine pathways.

Interestingly, TFPI-2 was detected in atheroma, in close proximity to tissue factor and factor VII, and also to plasmin/plasminogen on macrophages and on ECs, suggesting that TFPI-2 may be significant to the functional regulation of plasmin activity and proteolytic mechanisms in atherosclerotic lesions [ 42 ].

When generated, each agent is also given several personal characteristics that may be significant to matching (gender, birth year, and topic of interest) [ 4 ].

Whatever the reason why we have had a higher expression pattern in laryngeal carcinomas, the deregulation of this fundamental miRNA in its regulatory network may be significant imply on being the transformation biomarker for the laryngeal tumors.

This observation suggests that in a larger cohort the trend observed may be significant.