“may be significant”

15 , 19 There may be significant differences between the biomechanical behavior or properties between different ethnic groups, such as those of Caucasians (where the bulk of the literature is from) and Southeast Asian knees.

This finding may be significant if observed in advanced CRC, as it highlights a potential vulnerability which may be exploited therapeutically using the combination of agents that cause DNA single strand breaks and PARP inhibitors.

A significantly attenuated neurotoxicity in nontransgenic mice (i.e., very little loss of dopaminergic neurons with the dose of MPTP causing ∼50% reduction in our study) observed in this study suggest that there may be significant strain background and/or other transgene specific effects [27] .

Some of the same adverse health effects have also been observed among farmers' fami- lies and the general population living in agri- cultural areas (1,2,4-7), although specific exposures were not evaluated in most studies. Farm families and rural residents may be exposed to agricultural pesticides because their residences are adjacent to agricultural land and this type of indirect exposure to pesticides may be significant.

1 Third , a total serum IgE level above 100 kU/L may be significant under the age of 6 years but may not always indicate IgE sensitization or allergen sensitization as it is discussed.

Increased accumulation of apoptotic material may be significant if clearance mechanisms are weakened in individuals with autoimmunity.

Since colon adenocarcinoma (COAD) is a common age-related digestive system tumor associated with obesity, this may support CDKN2A as a prominent biomarker for different CRC conditions and may be significant for the prognosis of cancer predisposition during early adulthood.

Exposure and Confounding Variables - Incomplete Capture of Healthcare Exposure: The study does not account for non-inpatient healthcare exposures (e.g., outpatient or clinic visits), which may be significant, especially for infants. - Antibiotic Exposure Assessment: Reliance on patient recall for antibiotic use could introduce misclassification bias.

First, the issue of recall bias may be significant, as it often appears with more complicated behavior or when something happened 20–30 years ago.

Additionally, it may be significant that suppression of the BS splicing defect also resulted in higher levels of pSer2 RNAPII toward the 3′ end of exon 2 (amplicon 5; Figure 4 E and Figure S3 E) as was noted earlier for Ribo1, suggesting that this too may be splicing dependent.

Despite conidia dispersal via mite feces being unlikely, dispersal on the body surfaces of individuals may be significant ( Wallwork, 1983 ; Bernini, 1986 ; Paine, Raffa & Harrington, 1997 ; Hubert, Kubátová & Šárová, 2000 ; Ocak, Dogan & Ayyildiz, 2008 ).

Interestingly, the upregulation of NNMT was found to be inversely correlated with tumor size in renal clear cell carcinoma, suggesting that the enzyme may be significant in an initial phase of malignant conversion [ 32 ].

Perspectives Histamine and H 2 receptors may be significant contributors to aldosterone synthesis and release under normal and pathophysiological conditions with elevated circulating levels of angiotensin II.

There may be significant potential here for development in terms of both digital solutions and geriatric care.

Concussions often are incorrectly deemed even by some physicians as minor injuries without obvious evidence of damage to the brain, (Genuardi and King, 1995 ) yet there may be significant short-term and long-term consequences to suboptimal concussion management.

There can be physiological costs associated with TTX resistance [ 82 , 83 ], and the cost of maintaining TTX-producing bacteria may be significant, as it is in other mutualistic relationships [ 84 , 85 ].

Increases in soil-metal levels may be significant in cases of localized pollution such as in disposal of bottom ash and scrubber wastes from fossil fuel combustion, industrial wastes and municipal sewage sludges re- sulting in detectable increases in plants.

We believe that the potential impact on clinical services of such a device may be significant, particularly within the public health sector where radiology consultant support for immediate reporting and hand-held ultrasound may be limited. 5.

It may be significant for these prospects that long-range polariton propagation in the linear regime has already been demonstrated in GaN quantum well waveguides 47 .

Furthermore, human exposure through drinking water in contaminated areas and dust in indoor environments may be significant ( Emmett et al. 2006 ; Haug et al. 2011 ; Shoeib et al. 2011 ).

The implications of species occupying warmer or colder temperatures than their optimum may be significant for bioenergetic predictions and ultimately management.

For this reason, it is important to identify the factors affecting eczema development in early childhood, which may be significant at the beginning of the “atopic march”.

22 Yet, the worsening of depressive symptomatology after hospital discharge, in our study, may be significant based on significantly elevated nonsomatic scores in the HG.

The ICU is a data-rich environment at risk for data overload, and there may be significant benefit to safety and quality of care from decision support applications, medication administration systems and computerized order entry [ 24 ].

Hypothesis 2: There may be significant associations between common psychological health disorders .