“may be significant”

The studies reviewed in the final two sections of our paper suggest that these effects may be significant, but further work is needed to explore their full extent and assign consistent economic cost to them.

Patient engagement in study design is simply an invitation to be heard; risks are minimal, and there may be significant benefits for the young person, who might then better appreciate their own impact and agency.

In this context, it may be significant that both Irgb6 and Irgb10 can load, albeit inefficiently, onto T. gondii vacuoles in the absence of other IRG proteins ( Hunn et al. , 2008 , Fig. 7 and J.P.

Even though its applicability may be limited, this assessment may be significant to DA scientists given the complexity of DA in an innovative environment.

This difference in CK2 distribution may be significant with regard to its biochemical function in cancer.

Then the level of Dicer1 in the Nac was upregulated as the target of miR-124, which may be significant as the expression of Dicer1 in several brain regions is related to the response to abused drugs ( Mulligan et al., 2013 ; Liu et al., 2019 ).

Furthermore, several lines of evidence suggest that, across sexes, there may be significant differences in etiological pathways and psychological risk factors for psychopathy ( Cale and Lilienfeld 2002 ; Falk et al. 2014 ).

For instance, the glyoxylate cycle (PWY_GLYOXYLATE.BYPASS) and the super pathway of menaquinol-6 biosynthesis I (PWY.5850) may be significant for maintaining kidney health and defending against disease invasion.

Therefore, it’s possible that only one type of interaction effect may be significant.

Because of its potential function in the presynaptic modulation of catecholamine release [ 33 ], the existence of β2-adrenoceptor antagonism may be significant.

The reduced expression of 10 genes frequently observed in cancer each induce CIN and therefore may be significant, yet currently unappreciated drivers of neoplastic transformation and cancer progression.

While Klotho levels of the recipient and donor before transplantation may be significant, Klotho levels measured after transplantation are not associated with decline of renal function in our cohort.

Furthermore, there may be significant opportunities for practice improvement in measurement, treatment and monitoring of intraoperative glucose.

Third, there is currently no internationally agreed upon classification standard for vitamin D deficiency, and as such, there may be significant variations during reporting.

Even a point mutation may be significant for the occurrence of a certain disease.

CBP increases organ damage by stimulating inflammatory pathways, so there may be significant differences in the incidence of complications between patients who received CBP and those who did not ( 21 ).

Even though they showed a significant correlation (r 2 = 0.51) between longitudinal relaxation rate of the blood and Hct measured from venous blood, there may be significant difference in actual ECV and synthetic ECV for individual patients, specifically pediatric patients and young adults [ 17 ], affecting the ability to detect relatively small differences in ECV between normal and diffuse disease or treated vs non-treated subjects.

And while LRRK2 neuropathology typically reflects “usual” PD pathology, with prominent synuclein inclusions and nigral cell loss, there may be significant variability in neuropathological findings leading some patients to be reclassified atypical PD despite having usual clinical presentations ( Uitti et al., 2004 ).

This evolutionary connection may be significant for the phylogeography of the Mediterranean and have implications for research on other terrestrial animals.

Serum 25(OH)D concentrations usually tend to decrease with age, which may be significant in this COVID-19 pandemic, since case-fatality rates (CFRs) increase with age ( CDC Weekly C, 2020 , Vásárhelyi et al., 2011 ) .

Possible implications of this variability may be significant in understanding the evolution of Archaea and Bacteria in diverse and competitive environments.

Therefore, the association of PWM-PCP with CGI may be significant, and CGI-related PWMs may play important roles in housekeeping regulation.

Conclusions The study highlights that age, employment status, and a family history of anxiety disorders may be significant predictors of GAD in peripartum period.

This suggests that there may be significant correlations when examining abundance and rainfall/ temperature at a daily or weekly level.

As Figure 2A shown, the RNA expression from all samples clearly shows two different distributed clusters, from RIF patients and fertile control respectively, suggesting that there may be significant differences between RIF patients and the fertile controls in terms of RNA expression level and biological function.