“may be significant”

Because the prevalence of rheumatoid arthritis and periodontitis increases with age, inflammatory bone disorders may be significant sources of covert systemic inflammation among elderly people.

The convergence of multiple pathological drivers may be significant in explaining the role of some of the risk factors in glaucoma, in particular ageing which renders the retina more susceptible to damage; possibly as a result of reduced mitochondrial efficiency and lowered resistance to external stressors [47] .

Note that there are scenarios in which the autocorrelation term may be significant, and in these cases ISAM processing has been shown to mitigate this artifact via a blurring effect [ 13 ].

Genes targeted by deregulated miRNAs may be significant to psoriasis pathogenesis.

Given that the toxicity of amiR elements may be significant [ 42 , 43 ], target gene silencing was likely to affect only a subset of Fah-corrected NRas G12V expressing cells in regenerating liver tissue.

The acquisition of a frameshifted mtrR allele may be significant.

Most previous studies also do not account for uncertainty in census counts, though there may be significant error or privacy noise at smaller spatial scales 15 .

The effect of dental wear in the case of Chagyrskaya 64 may be significant due to the advanced age of the individual [ 26 ].

Since NSP4 is the most important and multi-functional protein of RV[ 6 ], analysis of this gene and its protein in clinical samples may be significant.

2 , 3 , 4 Studies suggest that the systemic effects of CVD may be significant drivers of the deterioration of other conditions, thereby increasing the incidence and mortality of related diseases. 5 In recent years, the potential link between CVD and cancer has emerged as a popular research topic.

There may be significant difference between male and female regarding the ADR prevalence due to factors such as body mass index, fat composition, hormonal effects, drug susceptibility, or genetic differences in the levels of enzymes ( Haile et al., 2013 ; Rukmangathen et al., 2020 ).

Moreover, there may be significant evolutionary costs that offset any such benefit, such as the relatively high energetic cost of maintaining brain tissue ( Aiello & Wheeler, 1995 ).

In further follow-up, the practical implications of the obtained results may be significant in cases of infiltrative diseases of a single lung, with the development of V/Q mismatch, or in predictive assessment of qualification for procedures known as resections greater than pneumonectomy [ 56 ].

Although the initial expenses linked to specialized surgical procedures and postoperative care may be significant, the possibility of sustained pain relief and enhanced patient quality of life holds the potential for long-term financial benefits.

These differences may indicate the contribution of circRNAs to the formation of a transcriptomic response specific to each brain region and may be significant for cellular recovery after stroke, leading to the development of new treatment strategies. 2.

96 Already in many publications of early structural work it has repeatedly been assumed that “ there may be significant bonding interactions among the gold atoms in these solids ”. 97 Such “ low‐dimensional Au⋅⋅⋅Au interactions ” have also been held responsible for the unusual absorption and emission characteristics of alkali dicyanoaurates(I) under high pressures (20 kbar).

Further, once acquired, there is an increased risk of spreading infection through societal and cultural factors including that HCWs touch a wide variety of strangers, travel more widely, and may be significant public figures who have large traditional burials.

Moreover, controlled-release formulations may be significant contributors to prolonged high serum concentrations.

Due to the large area of the Great Lakes, there may be significant differences in water levels even in different regions of the same lake (a comparison of the in-situ data of different stations found that there is an average deviation of 2–5 cm between different stations in the same lake).

Our work demonstrates a previously undescribed role for MFAP5 and suggests that microfibril-associated proteins may be significant modulators of wound healing outcomes and scarring.

Notwithstanding limited evidence relating to varied attitudes, knowledge and concussion-responsive practices [ 49 ], this raises consideration that the type of head contact impacting the head may be significant in SRC prevention in soccer.

Given that sorption to AWI is the dominant sorption mechanism for PFOS, the temperature dependency of this process may be significant, potentially resulting in seasonal variations in mass flux to the groundwater at contaminated sites.

As per this study's findings concern, patient characteristics, including age, platelet count, and oxygen saturation status at admission, may be significant predictors of death in elderly patients with COVID-19.

Therefore, quercetin may be significant in controlling the pathogenic potential of P. gingivalis through interference with mechanisms involved in hemagglutination and hemolysis.

The conceptual framework underlying narrative therapy ( White and Epston, 1989 ) and narrative exposure therapy ( Neuner et al., 2002 ) is to view the collection of life events that a person has experienced as a library of personal stories and to recognize that a certain number of these stories may be significant determinants of identity, commonly known in the PTSD literature as “self-defining memories” (e.g., Conway and Pleydell-Pearce, 2000 ; Sutherland and Bryant, 2005 ; Singer et al., 2013 ).