“may be significant”

These differential impacts may be significant and necessary for clinical pathologists to decide whether to report IDC-P subtypes and for surgeons to make reasonable and individualized multimodal therapeutic schedules.

This additional factor may be significant for expanding the use of P-AscH - therapy for other forms of cancer.

While still appreciating that downregulating Lp-PLA2 in adipocytes may be significant in reducing systemic triacylglycerols and oxLDL levels, it should be stressed that, as lipid control is a multifactorial process, examining more than one mediator would enhance our understanding of the potential impact on lipid profiles.

13 , 14 , 15 , 16 Therefore, N‐glycans and sialic acid may be significant regulators for tumor cell adhesion to extracellular matrix, perhaps by altering the molecular conformation of integrin by steric hindrance, thereby modulating the function of integrin.

Conclusions Interfacing OFI sensing schemes in commercial, all-purpose laser diodes together with human body measurements are a real challenge for biomedical applications, especially in in vivo cases, where the instabilities in the sensing experiment may be significant.

pes into water, Ando and Sayato (14) showed that injection of 10 mg/L quantities of VCM into deionized water, followed by various concentrations of sodium hypochlorite, converted the vinyl chloride into chloroacetaldehyde and chloroacetic acid: H2C = CHC1 + HOCI -1 C1CH2CHO + C1CH2COOH It may be significant that additional chlorination did not appear to take place.

The utilisation of a plant, or a living being with a comparatively high degree of complexities, supplies data on potential DNA damage in a multicellular life, which cell cultures do not provide, even though findings may be significant because the genomes of cultured cells may be those of mammals, as in the case of a mouse bone marrow tissues [ 5 , 6 ], or even turned cell lines from humans [ 7 ].

In general, the mPFC and TPJ regions were commonly identified across both prosocial decision-making and prosocial choices, but other regions including the PCC, precuneus, and IFG may be significant in certain contexts.

Applying clinical criteria for graft rejection, this temporary opacification may be significant enough to be considered complete graft rejection.

Conclusions In conclusion, our study demonstrates that evaluation of changes in specific layers of macular retinal thickness and VD may be significant diagnostic indicators for AD.

If risk and protective factors in the diet can be identified, there may be significant low-cost benefits for children with ASD.

The analysed data resulted in statistically significant results with a p ‐value <0.001 and the heterogeneity at 50% suggesting that the meta‐analysis results may be significant in supporting the application of vancomycin at surgical sites to reduce the surgical site infections and eventually improve the postoperative conditions by reducing the long hospital stays. intra‐wound vancomycin surgical site wounds wounds management 3.2 Studies selection The present meta‐analysis concluded 19 studies after a thorough literature review for further analysis which were statistically significant.

The risk of disease transmission posed by these horses to riders, handlers and the general public may be significant and requires investigation.

In sum, the obtained results document differences in the biological activity of MSCs obtained from various tissues during long-term culture, which may be significant from the point of view of application in regenerative medicine.

It needs to be emphasized that with prolonged use of ART, there may be significant bone mass reductions.

The intestinal concretions of powder HMF may be significant enough to cause acute deterioration and warrant surgical intervention due to intestinal obstruction [ 24 , 25 , 26 ].

A role in regulating the balance of nutrition between mother and fetus(es) could also be important, in which context the fact that GH-like proteins are produced in the fetal side of the placenta may be significant, raising the possibility of evolution of the proteins being driven by fetal-maternal competition ( 11 ).

means of communication.” This effect may be significant even if inventor networks are local or microgeographic clusters exist.

Differences in the preference and motivation for exercising between women and men in this study may be significant mediators and network structures based on differential correlations between the exercise and non-exercise groups [ 18 ].

2010 ), that, to first order, column observations can be used for estimating surface NO 2 mixing ratios at the locations studied, and that information content in temporally-short observations may be significant enough to detect surface variability from geostationary space-based instruments (e.g.

Notably, 7 of the 9 contigs showing intron retention included intron 4 either alone or in combination with other introns and may be significant in terms of enzymatic activity.

As these microorganisms can adhere to titanium surfaces, they may be significant in the colonization of dental implants and subsequent infections [ 70 ].

Furthermore, when neonatal cries have been assessed in autistic infants, changes in duration and pitch have also been observed, indicating that these parameters are not only conserved across species, but may be significant indicators of neurodevelopment ( 13 , 37 ).

Using resistive methods (such as coaxial shunt current sensor), the primary circuits are directly connected to the sensing circuits, which may not be a major concern in low-voltage electronics; however, it is of greater concern in power electronics, where the common mode voltage difference may be significant between the various circuit components, highlighting the absence of electrical isolation.

28 This may be significant, as over 70% of breast cancer patients in most HICs are diagnosed in stages I and II, but only 20%–50% of patients in many LICs and LMICs are diagnosed at these early stages. 29 Although our projections did not capture the impact of increasing lifespan, rapid population growth or changing lifestyles (eg, urbanisation), especially in LICs and LMICs, we acknowledge that such demographic and societal transitions may lead to increased healthcare demand and shifting disease patterns, potentially straining limited healthcare infrastructure and worsening delays in diagnosis and treatment.