The complications of perfluorocarbon instillation noted in human subjects, including pneumothorax, impaired carbon dioxide clearance, and delayed excretion, may be significant barriers to the clinical use of liquid ventilation in ventilated infants with MAS.
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In the literature
But changes may be significant at the level of individual vessel.
In HIV-positive individuals without a history of cardiovascular illness, coronary microvascular changes should receive more attention since they may be significant mediators of subclinical myocardial dysfunction ( 90 ). 3.6.2.
However, soybean crude peptides contain many unknown peptide segments because of differences in amino acid composition, amino acid quantity, and spatial conformation between each peptide segment, and there may be significant or minor differences in activity [ 28 ].
Another related issue is that even when a study disaggregates gays/lesbians from bisexuals, men and women may be aggregated into a single group, and gender/sex is typically used as an adjustment variable in these studies [ 33 – 35 ], which can lead to misestimations since there may be significant gender/sex differences within a given sexual orientation (e.g. gay men vs. lesbians).
It may be significant that nonresponders generally exhibited higher alpha center frequency compared to responders, before and after PrTMS, as validated by paired t -tests between the two patient groups for pretreatment, and for weeks 1–9 of PrTMS.
This study may be significant since we are presenting meaningful results with objective measurements and analyses, especially since previous studies only used subjective indexes (such as photographic assessment to evaluate the treatment effect).
Lp(a) levels are inversely correlated with the size of the genetically determined Apo(a) subtype, higher plasma Lp(a) levels are related with smaller Apo(a) subtype size, and there may be significant variability in Lp(a) levels amongst people with a given Apo(a) subtype size [ 22 ].
It may be significant that the results were positive in all the cases in which jaundice was present.
Because exposed patients had more severe baseline disease and more significant disease worsening (automatic assigned CRISS score = 0), the lack of worsening of individual CRISS measures among the exposed may be significant in and of itself.
Since even small correlations may be significant, statistical tests assessing if the PRCCs are different from zero are also performed [ 19 ].
It is well known that different deformation algorithms [ 14 ] and even different settings in a single algorithm [ 15 ] may give different results when propagating dose, therefore there may be significant errors in dose propagation and there is no gold standard for dose accumulation available.
Even though the majority of these observational studies use multivariate logistic regression analyses to identify drugs that may independently increase or decrease the risk of delirium, such techniques cannot account for all the reasons why groups differ in the rates of delirium; depending on the covariates that are being controlled for in the regression models, there may be significant cross-study differences in the results.
This may be significant as it could change the structural properties of the resulting TLR4 or TLR5 receptor, and therefore alter function.
This is especially problematic in acute hyponatremia when there may be significant alterations due to the sodium loss in the urine.
Although a dynamic model with sequential data may be superior, the model in our study predicts mortality within a specific period, which may be significant.
Therefore, the impact of exercise routines on sleep quality and SRH may be significant.
Residual sludge disposal costs and environmental impact may be significant, and decreasing such costs, as well as the consumption of energy required for dewatering and drying, is a main issue for ensuring sustainable and safe disposal of sludge, having in mind the recent ban of some disposal options, such as landfilling, in many countries in Europe.
The possible impact on population health, particularly among subjects with psychiatric disorders, usually at risk for sexual dysfunction, may be significant.
These results demonstrated that taraxasterol protected cardiomyocytes against hypoxia, suggesting that it may be significant for treating heart diseases ( Wang et al., 2018 ).
On the other hand, if the psychedelic-assisted psychotherapy is delivered as intended, there may be significant barriers to treatment in terms of both accessibility and cost.
Because a sizeable minority of the Scottish adult population (35% men, 17% women) regularly drink at hazardous or harmful levels [ 33 ], and lifetime prevalence of self-harm is also substantial [ 53 ], the potential contribution of research on volitional phase alcohol factors to prevention and management of self-harm may be significant.
Because transdermal transfer bypasses the metabolization of bisphenols in the liver, this route of transmission may be significant for the total amount of bisphenols detected in urine or seminal plasma.
We hypothesized that genetic predisposition and variants may be significant risk factors for PCL tears.
Although the group comparison between healthy and diseased animals showed a barely significant difference, the difference may be significant if the number of samples studied could be increased.