Barely Significant
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“may be significant”

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In the literature

Reports using rituximab described remission off therapy in a shorter time frame (ranging from 2 months to 5 years) as compared to other medication combinations; this observation suggested that while the initial side effects may be significant, a shorter total duration of therapy may be possible with use of rituximab.
Management of Pemphigus Vulgaris.
Adv Ther · 2016 · PMC4920839
Screening for cis-epistatic regions (which may plausibly have evaded selective pressure) prioritizes biologically plausible results while de-emphasizing individual SNPs, which may be significant because of population selection biases, unless they cause exclusively late-onset phenotypes, such as age-related macular degeneration.[ 86 ] Avoiding strong model assumptions (additivity, independence) reduces model misspecification biases.