“may be significant”

Despite these limitations, the results of this study suggest that there may be significant benefits of SCPs for survivors transitioning from tertiary cancer centres back to primary care.

Further, as FPTC may be a heterogeneous entity, there may be significant differences in the degree of aggressiveness between different families within any given report of cases, rendering comparisons in series with small numbers of families difficult.

How it does this is not understood, although it may be significant that of 56 proteins reported to interact with WT PMP22 in an HEK cell-based proteomics study, seven have functions related to cholesterol biosynthesis or homeostasis. 7.4.

Moreover, soybean is also a crop that is highly sensitive to photoperiod and temperature, and there may be significant variations in regional adaptability and yield among different soybean varieties [ 4 , 5 ].

As with CDI cases, there may be significant underreporting of CDI-associated deaths in Germany.

In addition, these findings may be significant for the development of a workable model that creates synergy between the public and private health sectors to exploit the skills, resources, and capabilities of the broader public.

Intraoperative hemodynamic disturbances, such as hypotension and arrhythmias, may be significant and may result from compression and anterior displacement of the heart during blunt finger dissection of the esophagus through the posterior mediastinum, which interferes with cardiac filling and output ( 5 , 6 ).

Alternative sources within the Eurasian continent might also be considered; bitumen trade between the Black Sea and the Mediterranean is archaeologically attested in earlier periods [ 50 ] and although the source of this material is not proven its location on the inland river routes linking to the Baltic and North Seas may be significant.

Also, the histological subtype of each of these tumours was not able to be determined—this may be significant as perivascular wall tumours have previously been shown to recur less frequently [ 5 ].

At the same time, it may be significant for caregivers’ quality of life ( Morrison et al., 2020 ).

Young children’s home food environments are important determinants of obesity risk ( 10 ) , and caregivers’ misperceptions about the healthfulness of the food and drinks they serve their children may be significant contributors.

Therefore, our specific aim was to assess if CFS, was an independent predictor which has not been extensively described in existing literature as an efficient tool for assessing frailty, since this may be significant in determining outcomes for older patients.

ration of exposure/non-exposure periods 2) Did the authors ensure that there was at least a 60 day observation period after the final exposure day prior to ending the observation period? 3) The risk of violating the independence assumption between RD and antibiotic exposure (not relevant for FINTA) may be significant, especially for those patients who experienced an RD event in the pre-exposure (-60 to 0 days) period for 2 reasons: i) a RD in the pre-exposure period would intuitively reduce the risk of a similar event in the post-exposure period as a patient would likely have only half the risk (one eye) as opposed to 2 eyes which might be affected by the exposure, and ii) the odds of prescribing a FQ compared to another antibiotic in those with an RD even in the pre-exposure period might be significantly reduced due to pre-existing concerns.

This may be significant in samples containing smaller concentrations of nAb, where interpretation of the nAb test line as “negative” or “weak+” becomes subjective to individual judgement.

We provide some evidence that GGA may contribute to loss of female attraction, and this may be significant at the natural release rates and ratios which are difficult to replicate in bioassays.

These findings may be significant in providing a safer yet efficacious alternative to levetiracetam.

The contribution of large number of drugs used or their metabolites to the municipal sewage systems and ground water may be significant.

Regardless of the dust-source region or the agricultural region being impacted, the economic and possible human consequences that may result from ignoring obvious transoceanic routes of dispersion may be significant and, more importantly, may directly affect the ability of a region to optimally produce and sustain food supplies.

These results suggest that differences in body size, patterning, and camouflage strategy may be significant between these species [ 62 ].

Our results strongly suggest that ICV and IDV may be significant contributors to BRD.

We hypothesized that (1) there may be significant differences in the ecosystem N, P, and K cycling characteristics due to the heterogeneous effects of nutrient elements; (2) whole-tree harvesting would have a negative impact on the ecosystem N, P, and K cycling functions because whole-tree harvesting causes substantial nutrient loss; (3) whole-tree harvesting may regulate nutrient cycling functions differently due to the significant disturbances it causes to vegetation, soil, and the overall environment. 2.

Also, due to the large volume of distribution [ 39 ] and the high HCQ tissue concentrations as compared to plasma [ 41 , 42 ], immunosuppressive effects in specific tissues may be significant.

This may be significant as anti-ferroptotic agents, as well as iron chelators, may comprise viable treatment options for bvFTD and other dementias [ 93 , 94 , 95 ]. 4.

These findings suggest that even though patients with isolated TBI seem to have less severe EoT, the breakdown of the glycocalyx may be significant enough to be a contributing factor to poor outcomes.

It may be significant in this context that XEN cells do not express the transcription factor Oct4 [14] that is found in all cells of the early ICM [15] .