“may be significant”

Downregulation of miRNA-181a and overexpression of miR-132, miR-143, miR-145 and miR-155 in serum may be significant in SSc in the context of biomarkers. systemic sclerosis microRNA Polpharma Scientific Foundation This work was supported by a grant from the Polpharma Scientific Foundation. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement yes pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY 1.

It may be significant that these manifestations of developmental toxicity are similar to those that have been reported after exposure of the male gamete to a DNA- damaging agent (51,55).

DegP assists in proper folding of the maltose operon regulator MalS at low temperatures (between 28°C and 37°C), which may be significant given the increased expression of the mal genes in all of the evolved isolates and the low temperature at which our chemostats were run (30°C) [62] .

The higher rate of EC use among women in this study could be due to their higher knowledge and/or positive attitude which may be significant determinants of the use of ECs.

In the Wilcoxon test, ✘ indicates when the p -value is greater than 0.05 and the same distribution may exist between the two algorithms; otherwise, ✔ is used to indicate that there may be significant differences between the two algorithms.

Among the PM-responsive lncRNAs identified in PS and PR plants, only a small fraction (17 DELs) was shared by PS and PR plants ( Figure 3B ), which is consistent with our previous speculation that there may be significant differences in the transcriptional response between PS and PR.

This suggests different mechanisms are present in different cell types and in vivo that may be significant for the tissue-specific pathology of SMA.

8 Another mechanism is that eosinophils sustain elevated tissue factor (TF) expression during maturation, serving as a primary source of preformed TF in the blood, which may be significant for thrombogenesis in conditions of hypereosinophilia.

For instance, in lung adenocarcinomas, this loss of size control may be significant [ 54 ].

Thus, inhibiting local immune reactions during active inflammation may be significant in managing inflammatory ocular diseases [ 49 ].

Individuals’ traits or personalities, which reflect their characteristic patterns of thoughts, feelings, and behaviors, may be significant antecedents of their pro-environmental attitudes and behaviors ( Soutter et al., 2020 ).

Although there may be significant financial costs and administrative barriers, there is evidence from this study to suggest that PPI should be incorporated as early as possible in doctoral education and continued throughout the research project.

Thus, more investigations on the underlying molecular mechanism may be significant for timely surveillance as well as improved prognosis of breast cancer.

Even though the 7000RMS is considered a commercial off-the-shelf (COTS) system, there may be significant prework needed to understand the operation of the 7000RMS in conjunction with the preparation and planning that is required to execute testing and data collection.

The conflict free trajectories are sufficient from the aspect of distance travelled, time savings, and fuel consumption, but these algorithms do not take into consideration the area reserved for the conflict resolution and its minimization, which may be significant in dense sectors during severe weather appearance.

This limitation may be significant in this group.

Exposure conditions and test organisms need careful consideration, as, for example, there may be significant inter- and intraspecies variation in sensitivity, requiring the use of additional safety factors.

In addition, the combined use of nafamostat and heparin may be significant for enhancing positive effects on patients [ 15 ].

Thus, fecal microbiota may be significant for further investigation of the features of esophageal cancer.

The ratio of wall/fluid interaction may be significant only in smaller nanochannels, but, in general, it does not affect ion separation at the scale investigated here.

Further, diabetes and obesity may be significant confounding factors in terms of disease control.

These values are modest in comparison to global estimates of chemoautotrophic biomass production on the global ridge system (10 10 –10 13 g of biomass yr −1 ; McCollom and Shock, 1997 ; Bach and Edwards, 2003 ), yet may be significant in the context of local secondary productivity.

There is good reason to believe previously reported regional stillbirth rates may be significant underestimates.

The observation in this study suggests that the differences in traffic activities between weekends and weekdays are not significant in Rubindi and Kyebando but may be significant in Mbarara.

Considering the small number of included studies, there may be significant heterogeneity, so a random-effects model was used.