Barely Significant
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“may be significant”

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In the literature

Despite the advantages, nMS is not used to the extent of the more common biophysical methods, including those where there may be significant challenges such as X-ray crystallography, that requires proteins suitable for crystallisation, or NMR, where proteins are commonly isotopically labelled and high fragment stock concentrations are needed, that can frequently meet with insufficient solubility leaving many fragments unsuitable.
Third, contrary to the general notion that the benefits of anesthesia methods are more pronounced in major surgeries with aggressive tumor, 26 our study suggests that even in the context of a minor surgery such as TURBT, there may be significant oncological benefits associated with the choice of anesthesia method, especially in cancers with a high risk of recurrence.
Antibodies to substance P were used to indicate the presence of sensory nerves, suggesting that hyperinnervation and high levels of substance P may be significant contributors to active arthrofibrosis. 57 Current treatments and new therapeutic outlooks Non-pharmacological treatments Arthrofibrosis research has often focused on treatments that address the structural pathology of the condition.