“may be significant”

Additional parameters that may be significant—such as treatment adherence (whether patients took clozapine as prescribed), illicit drug use, and nutritional deficiencies—could not be accounted for.

Pandemic situations may vary from country to country, and there also may be significant cultural differences (e.g., Liu et al., 2017 ; Zhang et al., 2015 ) between countries' handling of the pandemics.

In either case, this may be significant as the 5’UTR contains many important regulatory elements that impact replication and translation as well as recombination events that generate the viral sgmRNAs ( Li et al., 2008 ; Zuniga et al., 2004 ) and therefore may impact viral fitness.

Depression and maladaptive cognitions may be significant mediators that could explain the relationship between psychological flexibility and IGD.

A study in Denmark found that as many as 30,000 flies may enter a broiler facility during a single flock rotation in the summer months (Hald et al., 2004 ), suggesting that the impact of insect vectors may be significant.

It may be significant that the MIF-like activity present in conditioned medium produced by cultures of transformed mouse cells has been attributed to plasminogen activator (16).

The intensity at the control line “C” in the cassettes may be significant weaker in samples with high FHAA titers.

In this case, even relatively small increases in mortality rates may be significant for populations of rare species, especially large, long-lived species with generally low annual productivity [ 10 ].

[ 21 ] indicated that while ART interruption may have limited effect on children in the short term, its impact may be significant during critical periods of neural development.

Abnormal results may be significant for diagnosis and treatment, and may call into question the reliability of the test results.

With inhalers costing the same as syringes and needles to manufacture, there may be significant economic benefit for pulmonary delivery, especially in drug resistant patients.

Wilson [ 20 ] was interested in factors that may be significant in successful co-operation between nurses, residents and families in nursing homes and Miller [ 21 ] examined factors affecting successful partnerships between nursing home and hospice.

This fact, especially in reference to the ideology remembered from the recent past, may be significant in the shaping of the professional image of the Polish nurse and midwife.

The selectivity of the cytotoxic effect and features of the mechanisms of tumor cell death may be significant factors that determine the potential use of acadesine in antitumor therapy.

However, in elderly patients where comorbidities may be significant, violating the thoracic cavity or the retroperitoneal space can have severe consequences; performing a posterior procedure only would, thus, be advantageous [ 15 , 49 ].

While it is conceivable that individuals, private entities, or university laboratories could produce such test materials, there may be significant difficulties with longevity of the supply, communication of relevant information about the materials, and distribution of the materials.

Clearly all of these phenomena may be significant in children with such pasts, but the presence of neurodevelopmental disorder such as ASD is an important alternative explanation for the child’s difficulties, with different implications.

Compared with these CTA scoring systems, there may be significant advantages in using the rCBV and rCBF for collateral assessment.

This study uses only published data, and therefore publication bias may be significant.

Note that most nomograms treat the identified variables independently in the risk calculation, even though there may be significant interactions among the model features that were used in the feature selection step.

This importance of this workflow improvement may be significant.

While the duration of anesthesia is often short, the cumulative effect may be significant.

In lieu of interfering with the production of inflammatory mediators and/or interfering with specific inflammatory entities, there may be significant opportunities to improve outcomes in COVID-19 patients by modulating important downstream effectors of these inflammatory signals.

It may be significant in this regard that initial dinucleotide formation is the rate-limiting step in primer synthesis.

It is not known whether there may be significant clinical differences in the vascular effects of different ARB or BB drugs in this situation, or whether any benefit is a class effect.