“may be significant”

The 4-position of the indole only permits the presence of smaller substituents before deteriorating or losing potency, but substituents at the 6-position of the indole may be significant and lipophilic.

Notwithstanding, the percentage of patients with positive autoantibodies may be significant.

28) Rarely, the degree of tracheal compression may be significant, leading to clinical symptoms and resulting in innominate artery compression syndrome. 29) In this condition, further assessment with cross-sectional imaging (CT or MRI) should be performed to delineate associated arch anomalies.

IV and V ), may be significant and not be reasonably modeled based solely on linear systems theory.

Although previous research indicates that the effect of habitual tea drinking on bone density is minor and does not significantly alter the risk of fractures in an American population[ 25 ], this particular variable may be significant in the Indian population as 90% of the cases and 81% of the controls were regular tea drinkers.

Employment Status Four of six studies suggest that employment status may be significant.

In general, different building roofs have different spectra and reflectivity due to material differences, so there may be significant differences in spectral and textural characteristics.

As chondrocytes are key players in cartilage degradation in OA, our study also contributes to identifying which ASU product components may be significant in explaining differences in the pharmacological activity of ASU products.

Vitamin D may be significant in reproductive organ tumors [ 261 ].

Studies recently suggested that the involvement of these pathways may be significant in cognitive decline.

This suggests that its role in the signal propagation mechanism in the protein family may be significant.

This means that we cannot model entanglement or protein–protein binding which may be significant in the later stages of thrombosis.

The length of the time frame may be significant, in that it allows more time for a CBD stone to be passed before IOC, thereby affecting sensitivity and specificity.

Fixation of such fractures usually requires an aggressive surgical technique; consequently, postoperative pain may be significant, resulting in delayed rehabilitation and prolonged hospital stay.

Further, the dose and timing of exposure may be significant factors influencing child outcomes [ 47 , 50 , 82 ].

These results may be significant, but since they are rather general we suggest that more study is needed to develop more specific antibodies to better elucidate the protein expression of TEAD4 in breast tumor samples in clinic.

1 Consequences of DDIs may be significant, like increase in toxicity of interacting drugs or morbidity and mortality rate; however, they are predictable and preventable adverse drug events. 2 , 3 Screening patients’ medications to detect DDIs can minimize the harmful consequences of the interactions. 4 Critically ill patients are at an inc

Simply put, the potential public health implications are astounding, and as further research better elucidates the relationship between air pollutants and functioning pituitary tumors, we suspect the impact may be significant.

These mechanisms may be significant (or may be less relevant), depending on the type of physical environmental setting where the choice of APF occurs.

Population‐cohort studies have demonstrated that there may be significant differences in mental health outcomes during pandemic by sociodemographic characteristics (e.g.

The EPO-S100 interactions revealed here uncover a higher complexity level in regulation of EPO-mediated processes, which may be significant for development of novel therapeutic strategies. 2.

Therefore, when an elective laceration is managed by an out-of-network plastic surgeon, the plastic surgeon should educate the patient that there may be significant costs incurred beyond which is covered by insurance.

The previously described immune host defense dysfunction may be significant, but may be less important than the combined effects of comorbid disease(s).

The family history may be significant in X-linked–dominant patterns for disproportionate short stature, leg deformities, dental abscesses, periodontal disease, and hearing loss along with osteoarthritis, enthesopathy, and (pseudo) fractures [ 2 ].

It is not known whether there may be significant clinical differences in the vascular effects of different ARB or BB drugs in this situation, or whether any benefit is a class effect.