“may be significant”

Although the exact developmental mechanisms of direct pathological causes of behavioral disorders are poorly understood, environmental challenges may be significant initiators of behavioral disorders [ 16 , 17 ].

Relatedly, studies have now shown that the discordance between p16 and HPV may be significant in oropharyngeal cancer [ 29 ].

These findings most likely indicate that the discovered mutations are not disease causing; however, they may be significant factors if CMCC is inherited in a polygenic manner. " 10 , 11 , 12 A detailed physical examination of the patient is typically used to make the diagnosis of CMCC.

However, the recently published AA Clinical Practice Guideline suggested caution since there may be significant variability in their diagnostic accuracy and moderate confidence [ 174 ].

There may be significant limitations on patients' QOL.

Identifying additional factors that contribute to poor sleep quality in patients with RA may be significant in improving their health-related QoL (HRQoL), a numerical score that can be measured using the 36-Item Short Form Survey (SF 36) [ 11 ].

However, it is difficult to ascertain what differences may be significant from these studies.

Given that excessive YAP activation has been associated with OA development [ 69 , 70 , 71 ], metabolic abnormalities such as DM may be significant risk factors for OA.

This type of understanding can help in anticipating that there may be significant health effects from dam building, irrigation projects, clearing of forests, etc. – an understanding that can guide preparedness and prevention efforts.

Receptor binding studies revealed existence of both ET A and ET B receptors in the P22 tumour and showed that ET A receptors are more abundant than ET B receptors, which may be significant for tumour growth.

These results may have implications for understanding how glaucoma patients are affected in daily tasks where crowding effects may be significant. glaucoma visual crowding visual function pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-p

This implies that the interactions from the molecule B′ are not essential for the formation of the HpDprA–dT 35 complex ( Table 1 and Figure 5 E), but may be significant for stability of ssDNA docking onto the target site of HpDprA.

This exclusive presence of the isomerase class may be significant because isomerases regulate ciliary beat frequency in airway cells (Phua et al., 2017 ).

Since Aβ 42 is more toxic, selective interaction with this peptide may be significant for further analyses.

Therefore, while such entropic contributions may be significant in other systems, our MD results suggest that they play a negligible role in the observed binding affinities in this study. 3.

There may be significant drawbacks with this method, however.

The reasons why this region is susceptible to NTDs require further research and investigation, but empirical data suggest that the disproportionate impact of poverty and new 21st century environmental changes may be significant drivers.

The importance of diet on governing the development and progression of osteoporosis may be significant, but has not been fully discerned, and the role of ω-9 as a potential disease mediator has not been largely explored.

It is important to note that these demands on muscle are not the only sources of physiological cost: work and power associated with accelerating limb masses for protraction and retraction may be significant; as may be the costs associated with activating muscle isometrically.

41 There also may be significant variation in these responses as assessed by concentrations in plasma/serum for ACTH, plasma/serum and saliva for cortisol, salivary alpha-amylase (a measure of autonomic adrenergic arousal), and physiological assessments of heart rate and heart rate variability, as a function of extent of chronic s

The panel recognized that the implementation of resources and cost of NIV may be significant barriers to the widespread acceptance of NIV in patients with stable hypercapnic COPD.

This finding supports our qualitative results, which suggest that long distances and travel times to KP-friendly facilities may be significant barriers for some FSW and MSM.

The initial investment may be significant, but its durability and low operational costs make it a cost-effective choice over time, particularly for applications requiring frequent and rapid screening.

Frame-Level Optimization In video object detection, there may be significant differences in the detection results for the same object between adjacent frames, resulting in sudden drops in confidence and bounding box jitters.

Hypothesis 2: There may be significant associations between common psychological health disorders .