“may be significant”

Finally, since research in neighboring countries with similar cultural factors is still scarce, our results may be significant for countries in the region as well as Lebanon.

Another major limitation to our study was that we made no assumption about contribution of THMs from different exposure routes (inhalation and dermal absorption through showering, bathing or swimming or other water use activities) which may be significant contributors to the overall exposure to THMs [ 31 ].

These findings suggest that impaired interoception may be significant for engaging in serious self-harm and that improving the connection with the body could help prevent suicidal behavior [ 24 ].

This may be significant as there were only three studies identified in the review that met the established inclusion criteria.

Given that there may be significant differences in the influence mechanisms among these dimensions, future research could conduct in-depth investigations into the micro-influence mechanisms.

It would appear then that the proximal promoter region of Cdc6 is responsive to Myf5 as well, and this may be significant in light of the observations described below (see Fig. 6 ).

Thus, even a modest decrease in RhoA activation in association with rictor gene-silencing may be significant in the bladder cancer cells.

The gas trapped in the amorphous silica particles during their formation process and for the ones with encapsulated drug may be significant in comparison to the m-SiO 2 particles which have an organised large porous network (average pore size 2.7 nm) where adsorbed gas or drug can leak uncontrollably.

Feelings of being valued less than other patients or persons in society was also a common theme – and although changing public perceptions may be significant challenge, facilitating an environment within the MOUD clinic more conducive to this patient population maybe markedly less so.

A descriptive analysis of symptom types and infant demographics is provided but no data is presented on caregiver characteristics (e.g., age of mother) or other potentially significant historical factors (e.g., previous infant death; birth order), whereas you present qualitative information (and literature) implying that caregiver characteristics may be significant determinants of the outcomes of interest.

However, the high prevalence of asthma among never-smokers (55.6% of asthma) indicates that environmental exposures in this community may be significant contributors to respiratory disease burden, independent of individual smoking behavior.

Preference Timeline Partner preference typically becomes evident by 2–3 hours into the partner preference test, and in some data sets may be significant at earlier timepoints.

Furthermore, the MLR model showed that age was an independent risk factor for mortality in these patients, but the age-associated comorbidities were not after adjusting for the above covariables, which may be significant in univariate analysis (Table 4 ).

However, there may be significant confounders present in this study given the prevalence of mental health disorders and likely concomitant pharmacologic treatment of these conditions; all of which are also known to affect men’s sexual health.

found that even those who may initially wish to co-operate with becoming an organ donor by default and feel encouraged by the law change, may also be strongly affected by individuals or “lone wolves” who publicly and vocally declare their decision to opt-out, suggesting the impact of comments which do not support organ donation or the change in law may be significant ( 30 ).

Nevertheless, insofar as stability and familiarity during childhood are protective for psychological health, these differences may be significant.

For example, interholoenzyme autophosphorylation may be significant at the high concentrations of holoenzyme within the spine ( Lucic et al., 2023 ).

The country has ethnic diversity, where over 2000 groups with different ethnic identities in genetic makeup and lifestyles cohabit.[ 6 ] There may be significant differences in the stroke population of North and South India, both in terms of incidence and risk factor profile.[ 7 ] Secondary prevention with a structured semi-interactive stroke prevention package in INDIA (SPRINT INDIA) trial was undertaken to ascertain the efficacy of a structured semi-interactive stroke prevention package in patients with subacute stroke to reduce recurrent strokes, myocardial infarction, and death.[ 8 ] This did not reduce the vascular events when compared to standard care.

On configuring a KT team, however, there may be significant difficulties in choosing suitable personnel, such as clinicians, nurses, coordinators, etc.

Although individual hesitancy towards the test itself or distrust of broader health systems may be significant drivers of lower testing uptake in more socially vulnerable communities, it is important to consider the broader logistical challenges that have interfered with community members’ intentions and abilities to engage in testing behaviors.

This may indicate that the changes in expression of M2R mRNA, M3R mRNA and protein, and α-7 nAChR protein in the inflamed gilt endometrial layer may be significant for the modulation of the inflammation by ACh.

Furthermore, the developmental PC correlation may be significant to the modification of glycolipids, which were not analyzed in this report, but have been implicated in specific stages of development and embryogenesis (Gerdt et al., 1999 ).

Emerging evidence suggests that chronic stress and related diseases, such as depression and anxiety, may be significant factors contributing to the development of oral dysbiosis, progression of periodontal/peri‐implant disease, and inconsistent wound healing following periodontal therapy. 125 , 224 , 225 , 226 Moreover, the stress hormone, cortisol, has been shown to directly induce shifts in the composition of the oral microbial community and in its gene expression profiles in vitro, which reproduces results found for the gene expression profiles of the oral microbial community in periodontal disease and during its progression. 94 4.

Do the genomic regions bound in both human and mouse correspond to regulatory regions in the vicinity of active transcription (that is, in close proximity to shared H3K4me3 peaks), whereas uniquely bound regions do not? In other words, do conserved binding events represent the functional sites? If this is the case, it suggests that once 'functional' cis -binding events are distilled from non-functional ones, there may be significant conservation in cis -regulatory networks.

Naturally, we suspect that there may be significant heterogeneity in Npas4 expression dynamics across the POMC population as well.