“may be significant”

These results also suggest that there may be significant levels of MDA- and acetaldehyde-derived antibodies, in addition to anti-MAA antibodies, in mice under normal conditions.

Amylase-trypsin inhibitors found in wheat may be significant dietary allergen activators and adjuvants due to the marked exacerbation of allergen-specific T-cell proliferation and cytokine production with TLR4 engagement. 137 Furthermore, nitrated amylase-trypsin inhibitors produced by tetranitromethane cause far greater proliferation of Th cells and production of Th1 and Th2 cytokines than unmodified ones. 138 It is worth noting that LPS, as a major component of Gram-negative bacteria, is also commonly used in non-infectious lung disease models, such as asthma which is discussed in this section.

However, it may be significant that in a study of 3640 individuals who were asked about their attitudes towards having a DTC personalised genetic risk assessment, those working for healthcare organisations were more concerned about potential results than others in the sample (Bloss et al. 2010 ).

Although there may be significant bias reflected in our results, as the vast majority (271 of 295) of respondents were male, this discrepancy—and that in the field as a whole—may have been a major factor behind the survey responses of female surgeons, for instance ranking hard work more highly and mentorship less highly than their male counterparts.

In asthma, as well as potential efficacy among patients displaying a neutrophilic endotype, the observed effects of DPP-1 on activating mast cell, lymphocyte and natural killer cell activation may be significant.

4 , the degree of cervical lordosis and the occupying effect of OPLL ossifying structures (red arrow) may be significant factors affecting backward spinal cord drift [ 25 , 41 – 44 ].

Even if only one group is a significant path, the difference between paths may be significant, and even if both groups are not significant, a significant difference between paths may exist.

However, despite such a small share of mixed friction, many researchers indicate that the values of these torque increments in the period of direct contact of opposite shells may be significant.

This approach was considered appropriate because each sample represents a distinct hydrochemical condition, and the influence of single observations may be significant in a small dataset 37 .

21 Overall, TRYCATs may be significant effectors of how oxidative and nitrosative stress and pro-inflammatory cytokines mediate their influence on CNS and psychiatric conditions.

Other people’s influence on young people’s treatment decisions may be significant without being obvious.

Therefore, the discovery of ways to inhibit the growth of the PrE and to promote the proliferation of EPI may be significant for obtaining authentic porcine ESCs.

Moreover, the effects of immunological factors, pro-inflammatory and pro-angiogenic cytokines, e.g., TNFα, IL-1β, IL-6/8, or VEGF [ 2 , 6 , 25 , 26 ], may be significant.

31 It is expected that there may be significant variability in the way multimorbidity is defined within included studies, 32 including in terms of which specific LTCs are included. 33 Based on existing evidence, the inclusion of diagnoses which may be variously considered as conditions or risk factors, such a hypertension, hypercholesterolaemia,

Therefore, dietary intake characteristics may be significant indicators for predicting overweight or obesity in men aged 30–40 s.

In addition, administrative savings for Medicaid through HIE may be significant.

The follow- ing are examples of the kinds of problems susceptible to laboratory analysis. While not fully meaningful in and of themselves, they suggest interactions which may be significant in wild populations. 1.

There may be significant international variability in both the stains used and the exact chemical composition of the dyes used—for example, we analyzed both Meyer's and Harris's haematoxylin, but other methods may be in use which have not been measured in this work.

EPR studies revealed that the bioreduction of nitroxides may be significant for their protective activity.

CTAGE4, initially described as a tumor-associated antigen in cutaneous T-cell lymphoma, may be significant in the context of clonal T-cell proliferation.

If confirmed in a larger set, this may be significant in terms of therapeutic decision-making, as these mutations often predict resistance to standard therapies and may guide the use of targeted or experimental treatments [ 19 , 24 , 33 ].

Of course, given a sufficiently powerful experiment, even very low values of R may be significant.

Metabolomics could provide useful insights to deepen our knowledge of PD aetiopathogenesis, to identify signatures that distinguish groups of patients and uncover responsive biomarkers of PD that may be significant in early detection and in tracking the disease progression and drug treatment efficacy.

1 , 11 , 12 There are few estimates of the prevalence and distribution of pathogens that cause GIT illnesses, which indicate there may be significant differences in the prevalence of certain pathogens in circulation in developing and developed settings. 13-15 Determining the prevalence of pathogens on a regional basis will assist in the development of appropriately targeted prevention and control strategies, identify gaps in surveillance and provide support for the strengthening of laboratory diagnostic capacity at the regional level.

Naturally, we suspect that there may be significant heterogeneity in Npas4 expression dynamics across the POMC population as well.