“may be significant”

(3) The definition of csPCa used in this study does not include all clinically significant diseases, because ISUP GG1 with high tumor volume load may be significant and ISUP GG2 with low tumor volume load may be insignificant.

Although the effect may be significant, it is not large (perhaps a mean of 2.3 to a mean of 2.9). *In line 391, there is no evidence here that segregation of signaling networks provides an advantage to tumors.

In addition, the ratio of I1670/I1690 reflects the enzymatic cross-links in collagen.[ 27 , 31 ] In the DM group, this ratio was significantly lower than in the control group, suggesting that there may be significant changes in triple helix structure of collagen, since enzymatic cross-links have a significant role of maintaining stability of collagen fibrils within bone matrix.[ 36 ] However, in the group treated with Ang-(1-7), this ratio was significantly higher, indicating that Ang-(1-7) prevents the impairment of enzymatic cross-links; therefore, the impairment of triple helix structure of collagen caused by DM conditions.

Our study suggests that this correlation may be significant, because we have shown that the human brain expresses neurogenesis markers in a continuous area between the hippocampus and hypothalamus. 26 This area is larger than previously thought and involves the circumventricular organs, where the BBB is absent.

Therefore, it seems that κ and λ FLCs may be significant diagnostic and prognostic biomarkers of selected diseases.

Nevertheless, deep sequencing analysis showed ADAR1 mutation signatures in minor viral populations that were inversely correlated with viral load, mortality, and incidence, suggesting that ADAR1 mutations may be significant [ 141 ].

Although production losses due to anthrax are estimated to be low (few dead animals), overall losses due to indirect losses may be significant ( 21 ).

In this study, we used bioinformatics to identify novel key apoptosis-related genes and miRNAs that may be significant in the treatment and prognosis of MI.

This omission may be significant if the age variable is a factor for the reported differences of DH between studies.

Additionally, β-catenin has been associated with epidermal growth factor receptor (EGFR) family members [12] – [16] and the stability of β-catenin and its TCF/LEF-activating function has been suggested to be regulated via tyrosine phosphorylation by the EGFR family [15] , [17] – [19] , which may be significant for breast carcinogenesis, since human epidermal growth factor receptor 2 (HER2) is overexpressed in about 30% of human breast tumors [20] , [21] .

However, what these data also show is that there may be significant variation in compliance with laws restricting sales to minors across states, communities, and by store types [ 9 , 12 ].

Inadequate Follow-up If the revision is reasonably close in time to the original operation, then there may be significant postoperative inflammation resulting in early fibrosis and impervious scar formation.

This partial inhibition may be significant considering the functional switch observed in this pathway during tumor progression, transitioning from a tumor-suppressive to a tumor-supportive role 70 , 71 .

We hypothesize that there may be significant functional differences in MFE between crustaceans and insects and that the more distant the species are from each other, the more obvious the functional differences are.

Stem flow produces a great concentration of water around the base of the trunk, which may be significant ecologically.

Thus, ultrasound may be a more sensitive measure of change and positive changes in the context of a negative MRI may be significant.

Since there is no effective antiviral therapy for COVID-19 yet, adjuvant intervention for the survival of critically ill patients may be significant.

These effects may be significant and relevant from a policy perspective and help inform the global violence prevention debate as to the role of economic empowerment programmes.

In Cyprus, the southeastern part of Europe, a few studies conducted mainly in children have indicated that allergies on the island are on the rise, especially in rural areas, pointing out that lifestyle and environmental factors may be significant contributors to this phenomenon [ 9 , 10 , 11 , 12 ].

It may be significant that in pathway B, LiH is generated in a step prior to aromatic pyridine formation.

So there may be significant causal paths between certain variables, but their correlation is not significant.

As a result, most or all of the general population in these areas was exposed to fallout which may be significant in the development of subsequent malignant neoplasms.

with a higher hospitalisation rate) may be significant.

The finding of elevated neurodynamic organization in the frontal regions during INTB may be significant as frontal regions have been implicated in the detection of unfavorable outcomes, error correction, and resolution of uncertainty, all of which might be expected to play a role during this critical procedure ( Ridderinkhof et al., 2004 ; Murray and Rudebeck, 2017 ).

Naturally, we suspect that there may be significant heterogeneity in Npas4 expression dynamics across the POMC population as well.