“may be significant”

The small caliber or disease (tortuous, calcified, stenosed or obstructed arteries) of the iliac arteries prevents femoral artery access in a number of candidates that may be significant [ 3 - 5 ] .

Given the broad role of Arg in viral promotion and immune regulation our results may be significant for viral oncology more generally.

However, it should be noted that HLM analysis tests for within-person coupling of hormone levels, which may be significant even if the trajectories of hormone change for the group differ in the run-up to and over the course of an athletic contest.

More importantly, there may be significant variation in polymerase dynamics between different in vivo settings.

There may be significant barriers to the implementation of EMMS in developing countries, especially in rural areas, including substantial upfront capital expenditure, digital literacy and availability, and the existence of a robust technological and workforce infrastructure. 24 A country's level of ‘development’ can be measured in many ways, with income and economic metrics commonly being used as indicators.

Our work confirms the importance of the downstream sequence, but shows that a positively charged region instead of a single residue is required for efficient Cdt1 proteolysis and thus there may be significant variation in the structure of CRL4 Cdt2 degrons.

The topical carbonic anhydrase inhibitors, in particular, have been shown to be beneficial adjuncts to prostaglandin analogs both during the day and night.[ 25 26 ] There may be significant interpatient variability in response to beta blockers, carbonic anhydrase inhibitors, and alpha adrenergic agonists as second agents following the use of prostaglandins.

This may be significant because OA-induced cell death is counteracted by the perinuclearly located GTPase of the immune-associated proteins 5 (Gimap5) protein [ 98 ]. 10.

The different effects of VPA on KCC2 gene expression in GBM cells that we have identified may be significant in several respects.

In addition, their influence on the development of the sensory characteristics of the cheese may be significant as they are one of the predominant microbial groups during the ripening process [ 7 ].

The influence of caffeine on dopamine activity may be significant in AD and PD [ 19 , 160 ].

Palbociclib’s cytostatic effect may be significant in generalizing this analysis to other treatments which are not cytostatic.

Likewise, the association between CSA and PTB is inconsistent, suggesting there may be significant mediators or moderators of this relationship.

Conclusion Both weight gain and weight loss may be significant risk factors associated with dementia.

The carbonate skeletons of marine macro-organisms such as echinoderms and mollusks tend to be overlooked in modeling the global CaCO 3 cycles in the oceans [57] , although their role may be significant [58] , [59] .

There may be significant adverse reactions, particularly of the GI tract and cardiovascular system, as a result of the high plasma concentrations attained [ 9 ].

which may be significant is I use the voice recognition software and I find that I can pace or walk and talk like I can think about what I’m saying.

Regression modelling and sensitivity analysis Regression analysis was also considered in this study to understand how the MRD model may be significant or less significant in an isolated population.

Machine learning methods suggest that Eisenbergiella and Coprococcus are key players in these changes and may be significant disease markers.

There may be significant health benefits for women to receive timely diagnosis, as women who are diagnosed later in life are more likely to attempt suicide ( 12 ).

Limitations in Application Process include: Individual Differences: Although the Sleep Depth Value (SDV) demonstrates a strong correlation with sleep depth and arousability, there may be significant variability in SDV values among different individuals, which could affect the model’s ability to generalize across a diverse population.

An analysis of the primary transcriptomic pathways identified several differentially expressed transcripts that may be significant in the context of inflammation and oxidant stress ( Figure 4 ).

Third, using mathematical models, it has been proposed that heritable genetic variants, in particular, the loss or gain of CpG motifs, that enhance phenotypic diversity likely improve reproductive fitness, and that such effects may be significant for evolutionary adaptation to shifting environmental conditions ( Feinberg and Irizarry, 2010 ).

Thus, promoting the degradation of HA may be significant in the recovery process.

This suggests that the measurement index of AS and the elderly population may be significant factors contributing to heterogeneity.