“may be significant”

55 , 56 Emerging research indicates that obstructive lung diseases may be significant pulmonary manifestations of rheumatic diseases, while the risk of SpA is more associated with a restrictive spirometry pattern, such as PRISm, and absence of increased risk in COPD. 57 This differential susceptibility might explain: (1) Disease stage relevance: PRISm represents an early inflammatory phase characterized by mild restrictive ventilatory impairment (FVC <80% predicted), often preceding overt COPD.

This may be significant given the importance of neutrophils in the host response to systemic fungal infection.

Overall, these findings indicate that biological risk profiles among Latinos vary by nativity status and country of origin suggesting there may be significant heterogeneity in the total burden of disease risk within the Latino population.

In some forms of fictional narrative, such as 1st person autobiographical fiction, there may be significant degrees of overlap between the historical author and the narrator, a fact which nevertheless does not detract from the importance of the distinction itself.

18 Third, MBPs include a broad range of curricula 19–21 , and there may be significant differences in their efficacy.

In addition, there may be significant publication bias in that negative studies may not be reported and the difficulty in doing controlled studies due to the substantial expense of growth hormone added to an already expensive IVF cycle.

The EE may promote neuronal regeneration and enhance the function of the contralateral cingulate gyrus after stroke by promoting angiogenesis, which may be significant for the recovery of neurological function after stroke.

The observation may be significant since the VT bioavailability in sheep of the TDF prodrug is nearly 100 times higher than for parent TFV [ 40 ].

There may be significant differences in diabetic foot self-care behaviors between people with diabetes who are more or less likely to seek health care, interface with health care providers, and receive treatment for diabetes.

Therefore, the physiological roles of diverse KCTD may be significant with regard to GPCR signaling.

82 Despite knowledge of the importance of the avoidance of weight gain in people with SMI, there is a paucity of evidence for the acceptability of metformin among people with SMI and, in particular, among younger people for whom factors such as pill burden may be significant.

Although recent advances in cancer therapies have led to better clinical outcomes, 3 treatment-related side effects may be significant and consequently may have an impact on treatment adherence, frequency of hospitalisations and related costs as well as patients’ and their carers’ health-related quality of life (HRQoL).

However, there are still limitations to consider, such as the unidirectional motion of DNA‐based robots and the inability to reverse the behavior‐changing process, which may be significant obstacles for future research.

The differences may be significant in the 1-, 2-, and 3-year DFS rates and reduce over time due to various factors such as the development of treatment resistance.

For long texts and time series, the symbol diversity may be significant.

Although the area belonging to these partially forested pixels is small in forested landscapes such as in Finland (i.e., forests are fragmented by differently structured forests rather than different LC classes), in other geographical areas fragmented by agriculture and forestry, the fraction of pixels belonging to these mixed classes may be significant.

It was also demonstrated that the GEM particles may constitute a platform for presentation of several antigens at the same time, which may be significant for immunization against pathogens with a high genetic variability, such as Campylobacter jejuni , a leading cause of food-borne gastrointestinal diseases (Kobierecka et al. 2015 ; Wyszynska et al. 2004 ).

Accordingly, the coinciding increase of CD73 in PDAC cells may be significant in promoting extracellular adenosine-mediated immunosuppression.

Although there was no significant difference of these products in both lung tissues and BAL cells with paired t -test analysis based on the three pigs, these changes may be significant given larger numbers of animals tested.

In addition, our study includes more recent SEER data, which may be significant as treatments for pancreatic cancer have rapidly evolved in more recent years.

This antigen has a limited distribution in hematopoietic B lymphoid cells which suggests that the GVL effect may be significant for this antigen without GvHD (Brickner et al., 2006 ).

remains uncertain but may be significant especially in debilitated patients [ 2 ].

Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .

A less than 1% complication risk may be significant in particular circumstances, i.e. vocal cord paralysis causing a hoarse voice during throat surgery is not acceptable for a singer.

Thus, cannabis‐induced psychosis‐like effects may be significant in the early detection of psychosis.