In particular, the significant CpG site detected in KOCOSS-NIH, considering BMI, smoking status, cell type heterogeneity, and batch effect was only one, cg21259808 of HYDIN, and cg03074225 and cg26186239 of EEF1A2, cg06458358 of ARHGEF10, cg08093537 of FADS2, cg00451635, cg07406359, cg06713374 of EMP2 showed marginal significance (Table 3 ).
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In Model 12, it demonstrates a positive correlation with election participation, but only at a marginal significance level.
4.5 Limitations and future directions One of the main limitations in the current study was that we were constrained by a relatively small sample size, therefore any interactions showing weak or marginal significance should be interpreted with caution.
The RANKL tertile increased as age decreased, although with a marginal significance ( p for trend = 0.051). 3.3.
Although PPARα , which is predominantly found in the nucleus, has only marginal significance in the upregulation of the HS over the TN group, RXRA , PPARγ and CD36 are significantly expressed.
The marginal significance of cement volume warrants further investigation with larger samples.
Marginal significance was found in the birefringence alteration between meridional and equatorial strains, where the mean birefringence elevation by meridional strain was higher than that by equatorial strain.
In this model, the group differences in cACC.R and PHC.R were attenuated to marginal significance after FDR correction, while the effect-size directions remained consistent (see Additional file 1: Results and Table 12).
For males in their 30 and 40 s, however, homozygous minor/minor genotype count of core clock genes with MAF < 0.3 was negatively correlated (r=-.12 without statistical significance, r=-.13 with marginal significance, respectively).
In addition, among patients with severe fibrosis, current smokers at the time of SVR had an increased OR for HCC compared with never smokers, with marginal significance (OR, 5.61; 95% CI, 0.97–32.63).
Significance in statistical analysis was given to nominal P -values of ≤0.05 with significant FDR ≤ 0.05, and marginal significance considered for FDR ≤ 0.15 (specified where applicable).
S1) as well as pleiotropy-robust methods, where similar effect sizes with at least marginal significance in both weighted median and MR-PRESSO analyses were observed (Additional file 1 : Table S7 and S8).
3 , most separated healthy lifestyle factors were negatively associated with the incidence of MAFLD, except that without heavy drinking demonstrated a marginal significance (HR, 0.95; 95% CI, 0.87 to 1.04).
Although no significant association was found between TLR4 and AGER expression and lymph node involvement, we detected a marginal significance of these markers in IBC compared to non-IBC subjects.
Formal significance of the full model and marginal significance for which constrained axes to be evaluated for candidate loci was performed with the anova.cca function and 999 permutations in the vegan package.
Although this difference approaches marginal significance, the confidence interval includes 0, which suggests it is not reliable.
Besides, the total fecal 5-HT amount was accumulated with marginal significance in PCD patients (Figure S8h), which suggested active serotonin biosynthesis in colon.
It’s noteworthy that antipsychotics with anticholinergic and/or antihistamine effects may impair cognitive function in SCZ patients 56 , potentially associated with a higher daily CPZ equivalent in low-performers, albeit with marginal significance.
Percentage of vegetation cover and TN had little effect on fish species richness in both water types, and neither did surface area in the lentic systems (marginal significance) nor water width in the lotic systems (fig.
Indeed, while PRL gene expression showed only marginal significance with better AEFS using Hu (1,139 patients) and Sorlie (783 patients) methods of classification (bc-GenExMiner 3.0), it was significantly associated with prolonged RFS using KM plotter database (580 patients) ( Figure S3 ).
Mortality was associated with age greater than 63 (p-value 0.0052) and hypertension (p-value: 0.0058) with marginal significance with gender (p-value: 0.0642), chest pain (p-value: 0.0944), and history of cancer (p-value: 0.0944).
6 This interaction was reduced to marginal significance when we based estimates of conception-risk category membership on reported dates without regard to women's estimates of how confident they were in those dates, F (3, 79) = 2.34, p = .08, d = 0.60.
In our study, the differential expression here was documented only for 3 of these 14 genes; for the remaining genes of this family, expression differences were not found even at marginal significance.
Except for the marginal significance of the difference in D 1 % of the esophagus, the dosimetric indices of other OARs were statistically equivalent between 4 D CK and 4 D VMAT .
The age showed marginal significance with a P value of 0.053.