“marginal significance”

Stratified Cox regression also confirmed that the high FIB-4 group (HR = 1.301, P < 0.0001) was a significant risk factor, while the low FIB-4 group (HR = 1.204, P = 0.0752) showed only marginal significance, with a log-likelihood ratio < 0.0001 (Table S8).

Considering that the association between ISR and LS BMD gains was attenuated to marginal significance in the multivariate model, whether ISR serves as an independent predictor of treatment response remains unclear.

We observed similar interactions of time and social anxiety, however, this has to be regarded with caution as the interaction of time and LSAS only reached marginal significance.

In this case, genotypes at two out of 10 SNPs are associated with variation in bacterial load against at least two different bacteria at a nominal α of 0.05, and a third marker has marginal significance.

However, at this early stage in a drug’s development, it is premature to reject an effective candidate due to marginal significance; a one-sided test was used whenever applicable due to the fact that the current analysis was interested in testing the benefits of ASP0819 over placebo as opposed to the benefits of placebo over ASP0819.

The best model was trained in the TCGA-P cohort, showing a significant prognostication with a marginal significance in the HS cohort and a numeric difference in the TCGA-S cohort (Fig.

However, unfavorable genotypes only exhibited a trend toward marginal significance.

Each association achieving statistical significance following multiple testing correction is then evaluated through multiple comparative pairwise mixed-effects linear modelling together with each tracked baseline (metadeconfoundR) or time course (longDat) covariate that also achieved such initial marginal significance.

Increased SSS was significantly associated with lower odds of overweight and obesity among Japanese (OR = 0.78, 95% CI: 0.62, 0.98, P value < .05) and South Korean (OR = 0.71, 95% CI: 0.57, 0.87, P value < .001) females in simple models; however, the odds diminished to marginal significance for Japanese females after adjusting for covariates.

However, the p value ( p = 0.0303) is proximate to the conventional threshold of 0.05, indicating marginal significance.

Both for behavioral and ERP data, only main or interaction effects that reach statistical or marginal significance levels in comparisons of interest are reported.

The inclusion of covariates attenuated the association between the High Substance Use with Intermediate Symptom class and 12-month SUD diagnosis to marginal significance (odds ratio = 2.48) and nullified the association between the High-Symptomatology class and 12-month SUD diagnoses (odds ratio = 0.84).

Statistical significance was considered at α = 0.05, though marginal significance was considered at α = 0.1, and a result was considered highly significant at α = 0.01. 3.2.

Generalization to a different task was observed only in C1 and C5 (both svPPA), with marginal significance in C1.

Zhang et al reported a marginal significance in elevated susceptibility of miR-605 AG/GG genotype carriers to develop lung cancer than AA carriers; 21 however, we did not achieve a statistically significant result, which is consistent with the conclusion of Zhang et al in the overall association analysis of SNPs and risk of lung cancer.

On multivariate analysis using a Cox Regression model and entering PSA (p = 0.42) and age (p = 0.50) as continuous variables, and risk categorization (p = 0.61), T-category (p = 0.04), Gleason score (p = 0.53) and hormone use (p = 0.96) as categorical variables, only T-category displays marginal significance (table 6 ).

Results from CBCS recapitulated with marginal significance the established relationship between tumor subtype and patient genotype 11 : that tumors of patients with BRCA1 mutations are more likely to be Basel-like (6 of 16, 37.5%) than were tumors from patients of other genotypes (150 of 855, 17.5%; OR = 2.82, [1.01, 7.88]).

Histologically, a study of 1074 patients associates rs58542926 carriage with steatosis and fibrosis stage, attaining marginal significance for steatosis (OR = 1.38) [ 35 ].

The OR values of these seven SNPs were higher with experimentally determined genotype data in the replication phase (1.6 ≤ OR ≤2.1) than with imputed genotype data in the discovery phase (OR = 1.4), although their 95% CI overlapped. However, the association between the three IL10 SNPs and risk of BD was no longer significant in the replication phase, as the P values were much higher than a marginal significance level of α = 0.05 (Table 3 ).

Change reached marginal significance on the ADAS 11 when stratified by APOE ε4–negative subjects.

Both were detected as differentially expressed with marginal significance ( P adj = 0.036) and were not pursued further.

Although there was a positive correlation between the presence or absence of PTSD and RBD, which were the main outcome of interest of this study, there is a limitation that the p-value shows a marginal significance level of 0.049.

Additionally, two alternative statistic methods (Permutation test and Bayesian analysis) were conducted additionally to test how large the difference was between groups (Kruschke, 2013 ), particularly the marginal significance.

The effects at the 6-month follow-up reached statistical or marginal significance for health status, internalizing, externalizing and total behavioral difficulties, housing quality, and all three academic outcomes ( Table 2 ).

–6.70 ± 7.29 dB, P adjusted = 0.040), and the inferior and inferotemporal ganglion cell-inner plexiform layer (GCIPL) thicknesses tended to be greater in group A than in group B, with marginal significance ( P adjusted < 0.10).