“marginal significance”

In multivariate logistic regression analyses with factors shown as significant in the univariate analysis, female sex ( p = 0.004) remained significant while FGFR2 amplification ( p = 0.05) and TMB-high ( p = 0.06) showed marginal significance.

We may hypothesize that the already described heterogeneity of the cohort may be responsible for the marginal significance obtained with this classifier.

Children (3-20 years) trations, wood preservatives Murai et al., 1987 (67) PCB blood concentration (16 -- 123 Yusho patients (20-80 years) years after exposure) Bahn et al., 1980 (36) PBB workplaceexposure 124 Workers, male, middle-age Abbreviations: , increase; , decrease; --, no association; ( ), marginal significance.

However, while the direction of effects is the same, the individual effects and marginal significance of the two SNPs differ somewhat in the discovery and replication data sets (Table 3 ), so we would recommend some caution pending further replication.

Despite the marginal significance, gene sets regulating reactive oxygen species were enriched in the imiquimod-treated mice, suggesting adipocyte damage ( Figure 5 G ).

It should be noted that these regions showed marginal significance in the PVC analyses (Supplemental Table 5).

NHB race (HR = 1.43; P = 0.07) and low body mass index (HR = 1.98; P = 0.05) were associated with an increased risk of recurrence with marginal significance.

23.4 ± 8.9, p = 0.051) were higher in patients with COVID-19-associated symptoms with marginal significance.

Our study’s findings showed marginal significance for a correlation between biological reconstruction and postoperative deep infection.

The risk of recurrence or death was lower with a marginal significance (HR and 95% CI: 0.75, 0.56–1.01) in matched patients.

On the other hand, a previous study found that the small sample size may explain the marginal significance of the result [ 14 ], which may also explain the lack of a significant difference in participants' fatigue scores after the intervention.

For instance, the marginal significance of the indirect effect observed in the evening-type group might be attributed to an insufficient sample size, potentially resulting from random errors.

Considering that this is an exploratory study, marginal significance can also make us more convinced of the alternative hypothesis to a certain extent ( Pritschet et al., 2016 ), so we further conducted a mixed-design ANOVA under different interference task conditions.

Other variables, including age, APACHE II score, SOFA score, and norepinephrine use, showed marginal significance but did not reach statistical thresholds (Table 2 ). 3.3.

Inflammatory low back pain for more than three months, although with a tendency towards marginal significance (p-value 0.053), increased the risk of treatment discontinuation by 40.0% ( Table 3 ).

( 2018a ), where, although it appeared that the “modern” and “early” princes were lower in masculine behavior than the “middle” princes, only marginal significance was found.

Interestingly, the overall performance continues to improve between and within the S 2 and RET (main effects of session and trial) and the marginal significance for the interaction of group × trial is an indication for a possible within-session gain associate with the spaced training.

Although the OC2 ceRNA network exhibits marginal significance in the univariable analysis, higher scores of OC2 ceRNA network and PRC2/EZH2 signature associate with poor clinical outcomes.

Given its marginal significance and to preclude any potential bias, a trim-and-fill analysis was conducted.

Discussion In our metabolome-wide discovery analysis, we identified 11 plasma metabolites associated with COPD or lung function levels (FEV 1 /FVC) at marginal significance.

However, the correlation between VAT and N2 NoGo exhibited near‐marginal significance.

Given the marginal significance, we assessed the robustness of the enrichment using alternative approaches to define deleteriousness as a supplementary analysis, applying widely used functional prediction algorithms for missense variants: CADD, 69 MetaSVM, 70 M‐CAP, 71 REVEL, 72 and AlphaMissense 73 (Table S7 ).

Besides, non-gastric location ( p = 0.081) and high HSD11B1 immunoexpression ( p = 0.095) exhibited improved trend toward marginal significance. 3.5.

The marginal significance of “awareness” and “focus” make these experiences ideal candidates for further qualitative study.

When food insecurity, diet quality, and potentially inadequate intakes were simultaneously analysed with adjustment for covariates, food insecurity, poor diet quality, and suboptimal intakes of protein (marginal significance), folate, and iron all independently predicted poor mental health.