“likely to be significant”

Conclusions While VPA appears safe and well-tolerated in this initial pilot trial, these data suggest that weight gain and carnitine depletion are likely to be significant confounding factors in clinical trials.

This was especially true for genes where the absolute Z -score was >2, the genes that are most likely to be significant.

Industrial and Technological Innovations Cellulose-based gels are not only beneficial for environmental and medical applications; they are also likely to be significant in technological and industrial developments.

Whether these gains are likely to be significant remains controversial, particularly among those with undiagnosed depression.

Characteristics of Statistically Significant Correlations With Contact Depth For those measures where a statistically significant correlation with contact depth was observed, we attempted to determine whether there were any characteristics of the analysis that made it more likely to be significant.

Although the effects of severe and chronic malnutrition on surgical morbidity and mortality are not explored in the present study, they are likely to be significant. 19 20 Our study suggests that early weaning in acyanotic CHD may be a marker of fatigability associated with heart failure, which could help early recognition of CHD.

The quantity of unused, disqualified, expired medications as well us production by-product and residual that is discharged as industrial effluent is unreported, even though is likely to be significant.

Direct physical impacts at active sites on the spatially restricted hydrothermal vent fauna are likely to be significant initially, with the removal of habitat and a largely endemic fauna [75] . 1.6 Seamounts are very slow to recover from impacts Recovery of vulnerable species, and the assemblages which they form, from human impacts is predicted to be very slow in the deep sea [76] .

Health behaviours, whilst important risk factors for oral disease [ 8 ], are less likely to be significant in our model.

Although optimal housing for working dogs has not been established, the influence of housing on performance is likely to be significant.

For internally displaced people, who already have difficulty accessing adequate housing essential services and a decent income, the impacts of the pandemic are likely to be significant.

Globally, the number of older crime victims is likely to be significant.

38 It must be acknowledged that the practicalities of all children returning to school are complex, and there is likely to be significant anxiety for patients and families in specific scenarios.

51 In settings where the ED fulfils both primary and secondary care needs, the impact of these changes in healthcare seeking behaviour is likely to be significant, and may seriously undermine attempts to ensure universal health coverage. 46 The relatively small volume of discussion content related to ‘data’ is itself telling of the challenges for data collection in the ED.

An additional limitation of the phenology models used, which may have significant implications for their application to future climate scenarios, is their inability to capture the effect on plant growth and development of the projected increase in CO 2 concentrations: likely to be significant for C 3 crops such as the grapevine [ 74 ].

The connection between electric field and RhoA signaling pathways is likely to be significant in modulating fibroblast transdifferentiation in acute injury and tissue remodeling, which provides an innovative idea for the molecular mechanism of EF in promoting chronic wound healing.

Concluding Remarks Benthic community response to the impacts of sediment diversions is likely to be significant, based on benthic community response in geographically similar areas with restored freshwater flow.

Second, since the study by Jeoung was completed in 2012, there were likely to be significant equipment-related challenges to early screening of KC, particularly for patients in the earliest stages of disease development.

To identify genes that are likely to be significant for the studied biological processes, we set the p-value threshold to 0.001. 2) LIMMA We applied the LIMMA (Linear Models for Microarray) model to perform differential methylation analysis by fitting a linear model for the methylation levels of CpG sites as a function of the experimental sample groups [ 46 ].

Finally, we neglect any role of ammonium nitrate in the growth modeling, as chamber work shows that this process is highly temperature dependent and likely to be significant only at temperatures below those of this campaign. 49 , 53 Despite this, our modeled condensation rates match the evolution of the PNSD.

This kind of evolution at the physical and chemical level is likely to be significant in the period before emergence of replicating molecules, at which point the familiar kind of biological evolution commences.

When assessing micronutrient uptake, rather than concentration, the same pattern between the arable soils was seen, although the differences were less likely to be significant than they were for micronutrient concentration.

On the other hand, a project that involves developing a robust AI system is likely to be significant.

With rising standard deviation and decreasing sample size, the t -test is more likely to be significant.

There are additional countries that have highly productive (or potentially so) agricultural lands that have much slower growth in productivity; these countries are likely to be significant global players in crop production in coming years.