As with all modelling approaches, there is likely to be significant exposure misclassification, as modelling estimates at a point are unlikely to represent the true exposure of a mobile population.
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The use of multiple computational methods to select/filter those residues most likely to be significant adds confidence to their selection, and enabled the verification experiments to be better focused.
There are likely to be significant differences in dietary patterns according to geographical region, race, and culture.
The proportion of patients who lack capacity to make these decisions is likely to be significant.
Practical Implications and Further Research The implications of our findings are that, regardless of ICD-9-CM code classification, body-part treated, and the presence of surgical or non-surgical intervention, there are likely to be significant differences in physical rehabilitation utilization and treatment emphasis for injured workers between practice settings.
Whilst these observations are not direct proof that this protein is lipidated by transfer from the membrane, they do give a strong indication that acyl transfer from the membrane is likely to be significant in vivo .
Given the recent literature on CMD in the acute setting, 9 , 39 the proportion of unresponsive patients in MCS* is likely to be significant as well in the early days or weeks post‐injury.
Taste disorders are likely to be significant and highly specific symptoms in patients with mild to moderate COVID-19 and are known as important markers in primary infection.
Path analysis confirms that IPV, WPV and IS are all likely to be significant factors influencing the onset of depression.
These younger repeats still possess mobilisation ability 39 and are more likely to be significant contributors to the population variation and haplotypic differences through direct and regional positional effects.
This was necessary as in theory, primary outcomes are more likely to be reported in the abstract, and are also more likely to be significant as trials are often powered for their primary outcome.
The results of these tasks show that our approach outperforms the other state-of-the-art deep learning and genetic algorithm methods, where the z tests performed on the results of several experiments show that our method is more than 99% likely to be significant.
However, both estimates are likely to be significant underreports due to the exclusion of fatal unintentional drowning due to transportation and disaster-related causes.
Although it is too early to fully quantify the mental health consequences of the COVID-19 pandemic, inferences based on research from prior pandemics and natural disasters suggest that the psychological impact of the current pandemic is likely to be significant and longstanding ( Brooks et al., 2020 ; Raker et al., 2020 ; Wheaton et al., 2012 ).
Although, wide variations among populations may be the result of numerous factors, the influence of genetics is likely to be significant [ 65 ].
The authors of the GDs, using the GRADE system, 20 also categorised the recommendations by their strength in two levels: strong: the majority, if not all individuals, would opt for the suggested intervention; and conditional: there is likely to be significant variation in the decisions made by informed individuals.
The drug release data show that most of the PAR is likely to be released from the SLNs in aqueous/biological media, whereas there is likely to be significant retention of AMB and SSZ within the SLNs prior to absorption after administration.
These observations suggest that there are likely to be significant changes in Wnt signaling dynamics and metabolic programming of treated tumors, perhaps as a means of coping and surviving the loss of nutrient and cellular damage.
However the possible effects of body weight to RBED volume ratio are likely to be significant and this needs to be explored fully in future studies.
The aligned (sequential) occurrence of numerous members of a highly similar gene family within a compact genome is therefore relatively rare and highlights that their role within the nematode is likely to be significant.
Divergent selection is also likely to be significant among edaphic islands when there is environmental heterogeneity among different islands ( Weigelt et al. 2013 ).
The lack of general awareness and formal recognition by the government are both likely to be significant barriers to sustainability; parallel efforts to expand and professionalize mental health service delivery, such as by integrating mental health care into university training programs are also recommended [ 45 , 46 ].
As researchers continue to explore and refine these formulations, the impact on public health and patient well-being is likely to be significant.
The models provide useful insights into the structural aspects of these peptides and suggest features likely to be significant in influencing their binding and different pharmacological activities against their targets, with implications for drug development.
Given that in large sample sizes the χ 2 statistic is likely to be significant, the normed fit index (NFI), the Tacker-Lewis index (TLI), the comparative fit index (CFI), the goodness-of-fit index (GFI), the root mean square error of approximation (RMSEA) and root mean square residual (RMR) were calculated to evaluate the model fit in this study.