Hence, along with providing a more nuanced and deeper understanding of the stress-AL relationship, there is likely to be significant value for organisations in applying sex – and gender-based analysis when utilising the AL framework to investigate firefighter health.
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An alternative approach would be to identify patients with previous exposure and improve monitoring for early virological failure, although the problems of feedback of viral load results to patients and clinicians are likely to be significant in sub-Saharan Africa.
Furthermore, working days lost are only one of many societal costs of the pandemic and associated interventions; impacts on education, mental health, healthcare for non-COVID-19 patients, etc., are likely to be significant, but are not considered in this study.
In contemporaneous and future cohorts, inequalities in premature mortality are likely to be significant barriers to a necessary component of healthy ageing: survival into older age.
While the inclusion of groups such as people who inject drugs and gay and bisexual men in future reviews may increase the number and quality of studies, the impact of confounders is likely to be significant.
It is highlighted by the predominance of ST-45 in pets 32 , 69 , and its isolation in chicken 29 , 68 , 70 , environmental waters, wild birds 58 , 65 , 71 , and cattle 24 , 72 , indicating that chicken, ruminants or environment are likely to be significant sources of Campylobacter for pets through several transmission routes (e.g. food such as raw meat or offal).
25–30 Substituent effects at these sites are likely to be significant because of their impact on the geometric and electronic structures for putative supramolecular devices.
Although a chi-square test showed significant differences between the predicted model and the observed data, χ 2 (31, N = 612) = 48.52, p = 0.023, this test is highly likely to be significant when sample sizes are large ( N > 400) and when correlations are high, which conflicts with ideally conducting SEM on large sets of data.
31 , 39 Multiple factors are involved in the pathophysiology of prolonged AN, and combined approaches based on the behavioral, functional, and pathological changes of the neuroanatomical system are likely to be significant for future therapy.
However, there is likely to be significant reporting bias and the introduction of mandatory registries would enable more accurate monitoring across the region.
In addition, the PBWRA ratings provide guidance on when a difference between a GM plant and its parent is likely to be significant.
Nevertheless the trial has stopped and it is still likely to be significant.
The reason is that due to sampling variation, some studies will find an effect that is larger than the true population effect size; and those studies are more likely to be significant than studies that happen to find smaller, or more realistic, effects.
Genes with higher variation in spatial random effects tend to be less likely to be significant in a spatially aware model, as variability in the primary covariate can be increasingly explained by a spatially smoothed random effect.
24 , 25 Given that millions of outpatient antibiotic prescriptions are issued annually 26 and that the impact of those prescriptions toward the emergence of antibiotic resistance can persist for months, the contribution of outpatient antibiotic exposure to the overall burden of antibiotic resistance is likely to be significant and grossly underestimated.
Discussion Key findings Due to population ageing, increasing demands on residential care and home care services are likely to be significant over the coming decades.
s not change the fact that it is meant to reduce or prevent the transmission of arboviruses in humans, and thus, it is a public health “tool.” That raises the following question for poorer nations: How much will the GE insects cost and how will local or federal governments pay for them? The cost is likely to be significant for those nations and will eat into their budgets ( Box 2 ).
While even defenders of the model have admitted that the cost for implementation is likely to be significant, it is expected that once the platform has been implemented, costs for its upkeep should be comparatively low, especially if the tool is made available on a national level, as commonly suggested (Budin-Ljøsne et al. 2017 ).
P-adjusted values were less likely to be significant due to the large number of genes analyzed in the Illumina Human Methylation Bead Chip 450 K, making our statistically significant findings important, but likely under-identifying other potential statistically significant differential methylation patterns.
Bone loss from the spine during the first year of glucocorticoid therapy may vary between 3% and 10%; since the precision error of measurements is approximately 1%, a loss of more than 3% (the least significant change) is likely to be significant.
In more traditional case/control analyses, large bins are less likely to be significant because increasing binsize generally means more noise to mitigate the signal.
However, this finding must be treated with caution because the effect was very small, and small effects are more likely to be significant when the sample is large.
28 There are likely to be significant associations between a mother’s breastfeeding concerns during the infant’s first week of life and the cessation of breastfeeding, 29 highlighting the need for providers to address a mother’s concerns in the immediate postpartum period, either at the facility where delivery occurs, or at home, utilizing community health worker visits.
The host depletion by adaptive sequencing and thus enriching microbial organisms is likely to be significant for clinical samples, particularly if high levels of human DNA is expected (e.g., vaginal microbiome samples).
The limited reporting of adverse effects in neonatal transfusion trials, the quality of the studies identified as well as the risk of bias inherent in studies in this area are likely to be significant limitations to our review [ 9 ].